RESUMO
Bartter's syndrome, a rare disorder affecting the renal tubular potassium handling, is characterized by metabolic alkalosis, hypokalemia and renal salt wasting. Here we describe a patient with Bartter's syndrome with hitherto undescribed clinical features and also discuss the various possibilities leading to such variant of Bartter's syndrome.
Assuntos
Síndrome de Bartter/diagnóstico , Síndrome de Bartter/etiologia , Síndrome de Bartter/terapia , Humanos , Masculino , Linhagem , Adulto JovemRESUMO
Adenomyoepithelioma is a rare tumor characterized by proliferation of two different cell populations. These tumors have a variable biological behavior. Majority of them are benign but have a tendency to recur locally. Malignant transformation is rare in this disease and distant metastasis is rarer still. We report here an unusual case of bilateral adenomyoepithelioma at an unusual age and showing a remarkable response to an unconventional drug, tyrosine kinase inhibitor "imatinib".
Assuntos
Adenomioepitelioma/patologia , Neoplasias da Mama/patologia , Adenomioepitelioma/diagnóstico , Adenomioepitelioma/tratamento farmacológico , Adolescente , Biópsia com Agulha de Grande Calibre , Mama/patologia , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/tratamento farmacológico , Feminino , Humanos , Ultrassonografia MamáriaRESUMO
Acromegaly has several cardiovascular manifestations of which cardiomyopathy (CMP) and hypertension (HTN) are important and contribute to the increased mortality associated with the disease. Both these manifestations are reversible with treatment. However, very advanced CMP with severe systolic dysfunction has low likelihood of reversal. The reversibility is higher in young population and decreases as age advances. Also, the time required for these manifestations to resolve is about 1 year. Here, we describe a case in which HTN and advanced heart failure resolved in an aged patient within a very short span of 2 months from the time of presentation.
Assuntos
Acromegalia/complicações , Cardiomiopatia Dilatada/etiologia , Síndrome da Sela Vazia/complicações , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Gardner's syndrome is a variant of familial adenomatous polyposis. A multitude of extra-colonic manifestations including various endocrine tumors have been associated with this syndrome, the commonest of which is thyroid cancer. Majority of the patients with thyroid cancer and Gardner's syndrome are females. Here we describe a male patient with Gardner's syndrome who subsequently developed thyroid cancer.
