[The effect of kavinton, trental, sermion and kurantil on the blood flow rate in individual segments of the cerebral arteries]. / Vliianie kavintona, trentala, sermiona i kurantila na skorost' krovotoka v otdelennykh uchastkakh mozgovykh arterii.

The paper shows that intravenous administration of trental, curantil, cavinton and sermion to cerebrovascular deficient patients causes a decline in blood circulation rates in the extracranial part of the carotid arteries. Sermion exhibited a biphase reaction: an increase in the blood flow followed by a decrease 15-30 minutes after introduction in the carotid arteries. Trental and curantial act in the intracranial arteries as moderate vasodilators reducing blood flow speed and blood vessel resistance. Cavinton activates intracranial blood flow, especially in the cortical segments of the middle cerebral arteries. Sermion initially increases blood flow rate in the middle cerebral arteries, than decreases it, especially in segments M2 and M3. Cavinton and sermion intravenous infusions are beneficial in cases of arterial hypertension.

[Significance of subjective symptoms and diagnostic criteria in initial forms of cerebral circulation insufficiency]. / Znachimost' sub"ektivnykh simptomov i diagnosticheskie kriterii pri nachal'nykh formakh nedostatochnosti krovosnabzheniia mozga.

Piracetam was applied to the treatment of 60 patients with initial manifestations of brain circulation failure and stage I circulatory encephalopathy. The drug exerted a beneficial therapeutic effect by reducing high brain vascular resistance (both extra- and intracranial) and by increasing the lowered volume of pulse fluctuations. It made fibrinolytic blood activity and aggregation of formed elements of the blood return to normal. An appreciable antiatherogenic effect was discovered as well. It should be taken into consideration that in patients with a dramatic lowering of pulse fluctuations, the use of piracetam in a dose of 1.6 g/day may enhance headache. In such cases the dose should be reduced.