RESUMO
We encountered an unusual case of pemphigus foliaceus in which there were early clinical signs of dermatitis herpetiformis with eosinophilic spongiosis histologically. Numerous authors have appreciated that eosinophilic spongiosis occurs in early pemphigus foliaceus, usually in the preacantholytic stage when the lesions may clinically simulate dermatitis herpetiformis. Recognition of eosinophilic spongiosis may help differentiate early pemphigus from other vesiculobullous disorders.
Assuntos
Dermatite Herpetiforme/patologia , Eosinófilos , Pênfigo/patologia , Pele/patologia , Acantólise/patologia , Citarabina/uso terapêutico , Dermatite Herpetiforme/diagnóstico , Dermatite Herpetiforme/tratamento farmacológico , Diagnóstico Diferencial , Feminino , Herpes Simples/complicações , Humanos , Pessoa de Meia-Idade , Pênfigo/diagnóstico , Prednisona/uso terapêuticoAssuntos
Anticorpos Antibacterianos/análise , Testes de Fixação de Complemento , Imunofluorescência , Imunoglobulina G/classificação , Treponema pallidum/imunologia , Anticorpos Antinucleares/análise , Complemento C3/análise , Complemento C4/análise , Feminino , Humanos , Soros Imunes/isolamento & purificação , Imunoglobulina G/análise , Lúpus Eritematoso Sistêmico/imunologia , Masculino , Sífilis/imunologiaRESUMO
A patient had sensory radicular neuropathy. The patient demonstrated features characteristic of this entity: (1) recurrent trophic ulcerations of the hands and feet, (2) onset in early adulthood, (3) distal, dissociated loss of pain and temperature sensation far out of proportion to the loss of other sensory perceptions, and (4) complete sparing of motor function.