[Morphofunctional equivalents of the response of the adenohypophysis to limited physical activity]. / Morfofunktsional'nye ékvivalenty reaktsii adenogipofiza na ogranichenie dvigatel'noi aktivnosti.

Morphofunctional equivalents of the anterior main adenohypophysis reaction to hypokinesia lasting for 8 +/- 1 and 23 +/- 2 days are demonstrated. The experiment has been performed on 26 non-inbred male dogs. Restriction of the motor activity for 8 days results in increasing amount of beta-basophilic and chromophobic adenocytes and in decreasing amount of acidophiles. The high activity of the adenocytes is accompanied with structural signs of decreasing functional possibilities of the adenohypophysis as a whole. The general amount of cellular-vascular contacts reduces and there is a tendency to decrease the whole area of the capillary lumens. The reaction of the adenohypophyseal elements at hypokinesia lasting for 23 days is demonstrated not only as changes of cellular composition, but also in appearance of a large amount of colloid-containing pseudofollicles, atypical chromophobes and in a slight discomplexion of adenocytes. In animals of this group certain signs of a relative activation of the gland are noted as compared to the first period of hypokinesia: increase in the cellular-vascular contacts and in the general area of the capillary lumens. "Increase" of the contact layer of the adenohypophysial epithelial trabecule and decrease in beta-basophils and acidophiles amount, observed during the second period of hypokinesia, make it possible to conclude that most of the adenocytes are in the phase of secrete excretion.