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1.
Public Health ; 200: 59-70, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34700187

RESUMO

OBJECTIVES: This study aimed to summarise the effect of community-based intervention programmes on the prevention of cardiovascular disease (CVD) by reducing cardiometabolic risk factors. STUDY DESIGN: This was a systematic review and meta-analysis. METHODS: A systematic search in the PubMed database and screening of reference lists aimed to identify community-based CVD prevention programmes from inception up to April 2020. The mean differences and standard deviations for CVD risk factors, including blood pressure, lipid profile, blood glucose and body weight indices, were extracted and pooled using a random effects model. RESULTS: Screening of 11,889 titles/abstracts and full texts resulted in 48 studies being included in this review. The meta-analysis showed that community-based programmes have led to considerable decreases in systolic blood pressure (weighted mean difference [WMD] = -2.90 mm Hg, 95% confidence interval [95% CI]: -3.63, -2.16), diastolic blood pressure (WMD = -2.21 mm Hg, 95% CI: -3.12, -1.29), serum levels of low-density lipoprotein cholesterol (LDL-C; WMD = -8.88 mg/dl, 95% CI: -12.84, -4.92), triglycerides (WMD = -8.40 mg/dl, 95% CI: -12.10, -4.70), total cholesterol (WMD = -2.96 mg/dl, 95% CI: -3.10, -2.81) and fasting blood glucose (WMD = -2.06 mg/dl, 95% CI: -3.02, -1.10). A moderate decrease in body weight was also found with community-based CVD prevention programmes. However, community-based CVD prevention programmes were not associated with any significant changes in serum levels of high-density lipoprotein. CONCLUSIONS: The present study indicates that community-based strategies have successfully led to an improvement in CVD risk factors, particularly by reducing blood pressure, serum levels of LDL-C and triglycerides, obesity indices and blood glucose. The impact of these programmes on CVD is modified by the type of intervention and by different cultural and physical environments.


Assuntos
Doenças Cardiovasculares , Pressão Sanguínea , Doenças Cardiovasculares/epidemiologia , Doenças Cardiovasculares/prevenção & controle , LDL-Colesterol , Humanos , Lipídeos , Fatores de Risco , Triglicerídeos
2.
Community Dent Health ; 29(2): 149-53, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22779376

RESUMO

INTERVENTIONS: In 2007, the Finnish National Board of Education (FNBE) and the National Public Health Institute (KTL) recommended to schools that they quit regular selling of candies and soft drinks. OBJECTIVE: The aim of this study was to determine how and why such selling changed from 2007 to 2008 after the national recommendation. METHODS: Surveys were conducted using online questionnaires to all upper comprehensive schools in Finland. In 2007, 480 (49%) and in 2008, 507 (51%) schools answered the questionnaire; 319 (32%) schools participated in both studies. Schools were asked whether they sold candies, soft drinks or other sweet products and, if theyhad changed the selling of these products, why. The changes in selling were analyzed by using McNemar's test. RESULTS: Of the responding schools, 56% (n=267) and 46% (n=233) sold sweet products in 2007 and 2008, respectively. Of the schools responding both years, 56% reported selling sweet products in 2007 and 50% in 2008. Selling had decreased by 11% among the schools that took part in both studies. The main reasons stated for quitting selling these products were concern about pupils' health (40%) and the recommendation of the FNBE and KTL (38%). CONCLUSIONS: The national recommendation was followed by some decrease in sale of sweet products. For further progress, new actions, both policy measures and broader public involvement, may be needed.


Assuntos
Doces/estatística & dados numéricos , Comércio/estatística & dados numéricos , Guias como Assunto , Instituições Acadêmicas , Adolescente , Bebidas Gaseificadas , Sacarose Alimentar/classificação , Comportamento Alimentar , Finlândia , Serviços de Alimentação/estatística & dados numéricos , Promoção da Saúde , Humanos , Política Nutricional
3.
Nutr Metab Cardiovasc Dis ; 21(5): 380-9, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21470836

RESUMO

The prevalence of type 2 diabetes is increasing rapidly worldwide. Much of this increase in type 2 diabetes epidemic is related to the increase in obesity. There is now firm evidence from randomised trials that type 2 diabetes is preventable by lifestyle modification influencing diet, physical activity and obesity. This prevention effect is sustainable for many years after cessation of active intervention. The slow progression in the development and implementation of population-based strategies in the prevention of obesity and its most common and serious co-morbidity, type 2 diabetes, is of great concern. We summarise published implementation programmes and describe briefly the activities carried out in Finland. In the Finnish implementation programme for the prevention of type 2 diabetes (FIN-D2D), it was found that it is possible to prevent type 2 diabetes "in real life" in the primary health-care settings. We point out that innovative strategic guidelines and their proper implementation are needed to prevent the diabetes epidemic. Among the different tools, also taxation and other regulation to promote healthy food selection and good interaction with the media should be considered.


Assuntos
Diabetes Mellitus Tipo 2/epidemiologia , Diabetes Mellitus Tipo 2/prevenção & controle , Obesidade/epidemiologia , Obesidade/prevenção & controle , Serviços de Saúde Comunitária , Epidemias , Finlândia/epidemiologia , Promoção da Saúde , Humanos , Estilo de Vida , Atividade Motora , Prevalência , Atenção Primária à Saúde , Ensaios Clínicos Controlados Aleatórios como Assunto , Fatores de Risco
6.
J Epidemiol Community Health ; 62(5): 391-7, 2008 May.
Artigo em Inglês | MEDLINE | ID: mdl-18413450

RESUMO

BACKGROUND: Chronic diseases are now a major health problem in developing countries as well as in the developed world. Although chronic diseases cannot be communicated from person to person, their risk factors (for example, smoking, inactivity, dietary habits) are readily transferred around the world. With increasing human progress and technological advance, the pandemic of chronic diseases will become an even bigger threat to global health. METHODS: Based on our experiences and publications as well as review of the literature, we contribute ideas and working examples that might help enhance global capacity in the surveillance of chronic diseases and their prevention and control. Innovative ideas and solutions were actively sought. RESULTS: Ideas and working examples to help enhance global capacity were grouped under seven themes, concisely summarised by the acronym "SCIENCE": Strategy, Collaboration, Information, Education, Novelty, Communication and Evaluation. CONCLUSION: Building a basis for action using the seven themes articulated, especially by incorporating innovative ideas, we presented here, can help enhance global capacity in chronic disease surveillance, prevention and control. Informed initiatives can help achieve the new World Health Organization global goal of reducing chronic disease death rates by 2% annually, generate new ideas for effective interventions and ultimately bring global chronic diseases under greater control.


Assuntos
Doença Crônica/prevenção & controle , Saúde Global , Atitude do Pessoal de Saúde , Comunicação , Coleta de Dados , Países Desenvolvidos , Países em Desenvolvimento , Educação em Saúde , Política de Saúde , Humanos , Serviços Preventivos de Saúde , Fatores de Risco
7.
Eur J Ophthalmol ; 17(4): 550-6, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17671930

RESUMO

PURPOSE: To evaluate in a retrospective study the long-term usefulness of red 647 nm krypton and 670 nm diode laser for transscleral contact cyclophotocoagulation (CPC) in the treatment of therapy-resistant inflammatory glaucoma. METHODS: The authors treated 48 eyes of 38 consecutive patients (mean age 36.8 years, range 6-81 years) with therapy-resistant inflammatory glaucoma secondary to chronic uveitis (45/48), chronic scleritis (1/48), or combined scleritis with keratouveitis (2/48) using transscleral red 647 nm Krypton or 670 nm Diode laser. All eyes had failed maximum tolerated medical therapy and 19/48 (40%) eyes also previous antiglaucoma surgery. Laser power at the scleral surface was 0.35 to 0.45 W and the application time 10 seconds each. The follow-up was 42.8+/- 40.0 (range 2-145) months. RESULTS: The mean preoperative intraocular pressure (IOP) of 35.6+/-8.1 mmHg fell to 6-21 mmHg level in 75% after one or repeated CPC. Among adult patients this was achieved in 85%, among children in 54%. More than one treatment was needed in 52%. No cases of hypotony, phthisis bulbi, or other devastating complications occurred. CONCLUSIONS: Transscleral CPC using red 647 nm krypton or 670 nm diode laser is an effective and well-tolerated procedure for the treatment of therapy-resistant inflammatory glaucoma in adults. CPC can be considered before incisional antiglaucoma surgery with a shunt or antimetabolites is undertaken.


Assuntos
Corpo Ciliar/cirurgia , Glaucoma/cirurgia , Fotocoagulação a Laser , Esclerite/cirurgia , Uveíte/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Doença Crônica , Resistência a Medicamentos , Seguimentos , Glaucoma/tratamento farmacológico , Glaucoma/etiologia , Humanos , Pressão Intraocular , Pessoa de Meia-Idade , Estudos Retrospectivos , Esclera , Esclerite/complicações , Esclerite/tratamento farmacológico , Uveíte/complicações , Uveíte/tratamento farmacológico , Acuidade Visual
8.
Int J Clin Pract ; 59(4): 447-52, 2005 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15853863

RESUMO

This study assessed the degree of smoking cessation advice given by health professionals, before and after their participation in a smoking cessation study using bupropion-sustained release (bupropion SR, Zyban). A total of 690 physicians and nurses who had smoked an average of 10 cigarettes/day over the previous year and were motivated to quit smoking, were randomised in a double-blind manner to receive bupropion SR (days 1-3, 150 mg/day; days 4-49, 150 mg twice daily) or placebo for 7 weeks, with follow-up to week 52. All subjects received regular follow-up and brief motivational support throughout the study. Questions regarding their smoking cessation advice formed part of the study, with the aim of determining whether study participants became more proactive with their smoking cessation advice. A positive shift from baseline to end of study was observed with respect to the advice and support they gave to their smoking patients. These changes were not related to study treatment or current smoking status. An increase in advising patients to quit smoking and in offering cessation counselling was observed. Participation in a smoking-cessation study by physicians and nurses who smoke has a positive effect, regardless of study medication, in smoking cessation advice and counselling given to their patients.


Assuntos
Aconselhamento/normas , Pessoal de Saúde/normas , Promoção da Saúde/normas , Prática Profissional/normas , Abandono do Hábito de Fumar , Bupropiona/administração & dosagem , Preparações de Ação Retardada , Inibidores da Captação de Dopamina/administração & dosagem , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Motivação , Relações Profissional-Paciente
9.
Z Kardiol ; 93 Suppl 2: II37-42, 2004.
Artigo em Alemão | MEDLINE | ID: mdl-15021995

RESUMO

Globally most people die from noncommunicable diseases. Especially in developing countries noncommunicable diseases are on the rise, effecting especially poorer societal segments. The noncommunicable diseases contribute greatly to societal and economic losses and inequities in health status. The North Karelia Project was started in Finland to prevent noncommunicable diseases and with the main aim to curb the high mortality from cardiovascular diseases. In collaboration with the community, the health sector, the food industry and mass media, initiatives were started to promote a healthy diet, physical activity and reduce smoking. Over the last 25 years, the age adjusted mortality rate among men of 25-64 years of age from cardiovascular diseases fell by 73%, from lung cancer by 71% and total mortality fell 49%. Each country should plan and implement its own prevention programs, but lessons can be learned from the North Karelia Project. The paper discusses some key lessons and recommendation from the project for countries and for global work. In the last few years WHO has started to up-grade its work to fight noncommunicable diseases. Some initiatives are presented and discussed.


Assuntos
Doenças Cardiovasculares/prevenção & controle , Países em Desenvolvimento , Promoção da Saúde , Organização Mundial da Saúde , Adulto , Doenças Cardiovasculares/mortalidade , Causas de Morte , Comportamento Cooperativo , Exercício Físico , Feminino , Finlândia , Indústria Alimentícia , Educação em Saúde , Humanos , Masculino , Meios de Comunicação de Massa , Pessoa de Meia-Idade , Ciências da Nutrição/educação , Abandono do Hábito de Fumar , Taxa de Sobrevida
11.
Acta Ophthalmol Scand ; 81(1): 3-18, 2003 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-12631014

RESUMO

In most patients, chronic open-angle glaucoma is a slowly progressive disease. Eyes with very high intraocular pressure (IOP > 30 mmHg) represent an exception to this and should be treated and followed extremely intensively. As lowering IOP is, so far, the only means of treating glaucoma, the majority of research reports deal with the IOP-lowering effect of the treatment. The primary goal of treatment, however, is to prevent glaucomatous damage to the structures and function of the eye. The effectiveness of treatment is monitored with optic disc and retinal nerve fibre layer imaging and with visual field examinations. If the glaucomatous changes are progressing, more effective treatment should be given. In the course of follow-up, it should be noted that the changes in the optic nerve structure and function appear and progress at different time-points with delays of up to several years. The assessment of abnormalities is dependent on the examination method and requires a great deal of experience on the part of the examiner. The important risk factors in glaucoma are elevated IOP (even if IOP is within normal range in half of patients ), age, positive family history, exfoliation, race and myopia.


Assuntos
Medicina Baseada em Evidências , Glaucoma de Ângulo Aberto , Anti-Hipertensivos/uso terapêutico , Doença Crônica , Finlândia/epidemiologia , Implantes para Drenagem de Glaucoma , Glaucoma de Ângulo Aberto/diagnóstico , Glaucoma de Ângulo Aberto/epidemiologia , Glaucoma de Ângulo Aberto/fisiopatologia , Glaucoma de Ângulo Aberto/terapia , Humanos , Pressão Intraocular , Fotocoagulação a Laser , Fibras Nervosas/patologia , Disco Óptico/fisiopatologia , Doenças do Nervo Óptico/diagnóstico , Doenças do Nervo Óptico/fisiopatologia , Doenças do Nervo Óptico/prevenção & controle , Guias de Prática Clínica como Assunto , Fatores de Risco , Trabeculectomia , Campos Visuais
14.
J Hum Hypertens ; 16(5): 299-303, 2002 May.
Artigo em Inglês | MEDLINE | ID: mdl-12082489

RESUMO

Despite the evidence that smoking is one of the main predictors of the cardiovascular disease risk among hypertensive subjects, there are very few data available of the smoking trends of these subjects at public health level. This study assesses the trends in smoking and in smoking cessation advice given by physicians in the hypertensive and normotensive population in Finland during 1982-1997. The data were derived from four independent cross-sectional standardised population surveys conducted in 1982, 1987, 1992 and 1997 in the provinces of North Karelia and Kuopio in eastern Finland and the region of Turku-Loimaa in south-western Finland. Men and women aged 25-64 years, selected randomly from the national population register, were classified to four groups according to their blood pressure level and antihypertensive treatment status: normotensive, unaware hypertensive, aware but not treated hypertensive and treated hypertensive. The total number of participants was 24 083. In men, the prevalence of smoking decreased significantly in both treated hypertensive patients and normotensive subjects during 1982-1997, whereas it increased significantly in treated hypertensive women. The proportion of current smokers who had been advised to stop smoking by their physician was significantly higher in treated hypertensive men compared to the other subgroups of men (P < 0.001). The observed decreasing trend in smoking in men is encouraging, but the increase in smoking among hypertensive women taking antihypertensive medication warrants concern. In the future, the methods used for smoking cessation advice given by health care personnel should be intensified to make this effort more effective.


Assuntos
Hipertensão/epidemiologia , Fumar/tendências , Adulto , Estudos Transversais , Feminino , Finlândia/epidemiologia , Humanos , Hipertensão/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Fumar/epidemiologia , Abandono do Hábito de Fumar
15.
Eur J Clin Nutr ; 56(4): 352-7, 2002 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11965512

RESUMO

OBJECTIVE: To study whether Abacor, a product based on isolated soy protein with high and standardised levels of isoflavones and cotyledon soy fibres, was more effective in lowering total and LDL cholesterol than placebo. DESIGN: Randomised, placebo-controlled, double-blind, parallel group, single centre study. SETTING: Primary care in Joensuu, North Karelia, Finland. SUBJECTS: Subjects were screened from the patient database of the health centre; 30 were randomised to the Abacor group and 30 subjects to placebo. Eight subjects were withdrawn, six from the active group, two from the placebo group. INTERVENTION: The preparations were given as two daily liquid supplements in addition to the subjects' regular diets for 6 weeks. RESULTS: Abacor showed a statistically significant lipid-lowering effect as compared to placebo, although an unexpected reduction was seen in the placebo group. The estimated difference between active treatment and placebo was 0.25 mmol/l (95% CI 0.01, 0.50; P=0.049) for total cholesterol, corresponding to reductions of 8.3 and 5.1%, respectively. The difference in reduction of LDL-cholesterol was 0.27 mmol/l (95% CI 0.06, 0.49; P=0.014) and corresponded to a reduction of 13.2% in the active treatment group, and 8.0% in the placebo group. Abacor showed a rapid onset of effect, as compared with placebo. During a wash-out period of 4 weeks after treatment, the subjects returned to pre-treatment cholesterol levels. CONCLUSION: Added to a regular diet, Abacor significantly reduced LDL-cholesterol and total cholesterol. These beneficial effects occurred within 6 weeks of treatment.


Assuntos
Hipercolesterolemia/terapia , Proteínas de Soja/uso terapêutico , Adolescente , Adulto , Idoso , Colesterol/sangue , LDL-Colesterol/sangue , Método Duplo-Cego , Feminino , Finlândia , Humanos , Hipercolesterolemia/sangue , Masculino , Pessoa de Meia-Idade , Proteínas de Soja/sangue
16.
J Epidemiol Community Health ; 56(3): 167-70, 2002 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11854334

RESUMO

STUDY OBJECTIVE: The validity of self reported smoking in population surveys remains an important question. An associated question is what would be the value of measuring serum cotinine concentrations in such surveys to obtain validated smoking data. DESIGN: Cross sectional analysis of data on self reported smoking and serum cotinine among a random population sample of 5846 persons aged 25 to 64 years, who participated in the FINRISK-92 survey. MAIN RESULTS: Among self reported regular smokers, 97.2% of men and 94.9% of women had a cotinine concentration of 10 ng/ml or higher in serum. Of those participants who reported to have smoked at any time during their life but not during the previous month, 6.3% of men and 5.2% of women had a serum cotinine concentration of at least 10 ng/ml. Among never smokers 2.5% of men and 2.7% of women had detectable level of cotinine in their serum. The validity of self reporting was similar among subjects from different areas, ages, and socioeconomic groups. CONCLUSIONS: In a sample of the general population in Finland the validity of self reported smoking is high, and most of the few self reported non-smokers who had cotinine in their serum had only low or moderate levels.


Assuntos
Cotinina/sangue , Inquéritos Epidemiológicos , Fumar/sangue , Adulto , Atitude Frente a Saúde , Biomarcadores/sangue , Estudos Transversais , Feminino , Finlândia/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Autorrevelação , Fumar/epidemiologia
17.
J Cataract Refract Surg ; 27(12): 1992-8, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11738916

RESUMO

PURPOSE: To ascertain whether the exfoliation syndrome (EXS) is a risk factor for cataract development. SETTING: Helsinki University Eye Hospital, Helsinki, Finland. METHODS: This prospective study examined the development of lens opacities using the Lens Opacity Meter. Visual acuity and refraction were measured in both eyes of 63 nonglaucomatous patients with clinically unilateral EXS. After 5 years, 46 patients were available for follow-up. Case histories of 14 patients were recorded. RESULTS: During the 5 year study, the rate of conversion to bilateral disease was 22% and to exfoliative glaucoma, 30%. At the beginning of the study, the mean lens opacity was 23.5 opacity units (OU) +/- 6.7 (SD) in EXS eyes and 22.9 +/- 7.2 OU in fellow, initially nonexfoliative (NE) eyes; the difference was not significant. After 5 years, the mean opacity was 30.0 +/- 8.8 OU in EXS eyes and 26.9 +/- 8.3 OU in NE eyes (P <.001). In patients who remained unilaterally affected, the EXS eye had a higher opacity value than the NE eyes at the start of the study (23.6 +/- 7.3 OU and 22.7 +/- 7.2 OU, respectively) (P <.05) and after 5 years (29.9 +/- 9.0 OU and 27.0 +/- 8.5 OU) (P <.01). There was a significant myopic change in refraction over time in both groups. The mean refraction in EXS eyes was +1.02 +/- 2.48 diopters (D) at the start and + 0.11 +/- 3.06 D after 5 years (P =.0001) and in NE eyes, +0.99 +/- 2.25 D and +0.43 +/- 2.55 D, respectively (P <.01). At the start of the study, the mean difference in refraction between fellow eyes (refraction in NE eye - refraction in EXS eye) was -0.27 +/- 1.00 D. After 5 years, it was +0.32 +/- 1.44 D (P =.016), showing a greater myopic change in EXS eyes. CONCLUSION: The results show that EXS is a risk factor for lens opacification.


Assuntos
Catarata/etiologia , Síndrome de Exfoliação/complicações , Cristalino/patologia , Idoso , Idoso de 80 Anos ou mais , Catarata/diagnóstico , Extração de Catarata , Seguimentos , Humanos , Pressão Intraocular , Pessoa de Meia-Idade , Estudos Prospectivos , Refração Ocular , Fatores de Risco , Acuidade Visual
19.
Bull World Health Organ ; 79(10): 963-70, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11693979

RESUMO

Community-based programmes for prevention and control of cardiovascular diseases (CVD) started in Europe and the USA in the early 1970s. High mortality from CVD in Finland led to the start of the North Karelia Project. Since then, a vast amount of scientific literature has accumulated to present results and discuss experience. The results indicate that heart health programmes have a high degree of generalizability, are cost-effective and can influence health policy. In the 1980s the focus of programmes expanded from CVD to noncommunicable diseases (NCD), mainly because of the common risk factors. Attention has now turned to promoting this approach in developing countries, where the prevalence of NCD is growing. Theory and experience show that community-based NCD programmes should be planned, run and evaluated according to clear principles and rules, collaborate with all sectors of the community, and maintain close contact with the national authorities. In view of the burden of disease they represent and of globalization, there is a great need for international collaboration. Practical networks with common guidelines but adaptable to local cultures in a flexible way have proved to be very useful.


Assuntos
Doenças Cardiovasculares/prevenção & controle , Países Desenvolvidos , Países em Desenvolvimento , Serviços Preventivos de Saúde/organização & administração , Doenças Cardiovasculares/economia , Doenças Cardiovasculares/epidemiologia , Doença Crônica/economia , Doença Crônica/epidemiologia , Saúde Global , Promoção da Saúde/métodos , Promoção da Saúde/organização & administração , Humanos , Prevalência , Desenvolvimento de Programas , Avaliação de Programas e Projetos de Saúde , Fatores de Risco , Organização Mundial da Saúde
20.
Ophthalmology ; 108(10): 1801-7, 2001 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-11581052

RESUMO

PURPOSE: To evaluate the usefulness of the krypton laser for transscleral contact cyclophotocoagulation (CPC) in the treatment of glaucoma in young patients. DESIGN: Retrospective noncomparative interventional case series. PARTICIPANTS: Transscleral contact krypton laser CPC was performed in 27 glaucomatous eyes of 22 young patients (mean age, 10.5 +/- 5.6 years; range, 11 months-19.4 years). METHODS: The treatment was delivered by means of a fiberoptic probe with compression of the sclera by the probe. The power used was 300 to 500 W per application at the tip of the probe with an exposure time of 10 seconds. MAIN OUTCOME MEASURES: The primary outcome measure is a change in intraocular pressure (IOP). RESULTS: Of the patients who received CPC in both eyes, one eye was randomly chosen for statistical analysis. The mean overall follow-up time was 43.3 +/- 25.3 (median, 36.5; range, 1-82) months after the initial CPC. Preoperatively, the mean intraocular pressure was 35.0 +/- 7.9 mmHg (n = 22). After one or more CPCs, the mean IOP was decreased to 21.5 +/- 8.7 mmHg (n = 22) at 1 month (P < 0.001), to 23.4 +/- 8.6 mmHg (n = 18) at 3 months (P < 0.001), to 25.0 +/- 12.1 mmHg (n = 19) at 6 months (P < 0.01), to 22.1 +/- 9.1 mmHg (n = 16) at 1 year (P < 0.01), and to 22.6 +/- 10.3 (n = 11) at 2 years (P < 0.01). After one or more krypton CPCs, but no other glaucoma procedures, an IOP level of 8 to 21 mmHg or a decrease in IOP of more than 30% was obtained in 14 of 22 (64%) eyes at the last follow-up. No permanent hypotonia, phthisis bulbi, or devastating CPC-related complications were noted. CONCLUSIONS: Krypton laser CPC is a well-tolerated means of lowering IOP in young patients with glaucoma, but repeated treatments may be needed.


Assuntos
Glaucoma/cirurgia , Iris/cirurgia , Fotocoagulação a Laser , Adolescente , Adulto , Criança , Pré-Escolar , Seguimentos , Humanos , Lactente , Pressão Intraocular , Complicações Pós-Operatórias , Estudos Retrospectivos , Esclera , Resultado do Tratamento , Acuidade Visual
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