RESUMO
Trichinosis was experimentally induced in rats. The morphology of encystation of Trichinella larvae was studied in the striated muscles. The efficacy of albendazole was evaluated in different intensity of Trichinella larvae infestation in the striated muscles of the laboratory animals. Encystation was shown to cease at 21 days. Albendazole showed high activity against intestinal and encapsulated larvae of Trichinella, leading to 100% death of T. spiralis. Capsules and Trichinella larvae were described to be destructed after treatment with albendazole 15 mg/kg twice daily for 10 days.
Assuntos
Albendazol/farmacologia , Anti-Helmínticos/farmacologia , Músculo Esquelético , Trichinella spiralis , Triquinelose , Animais , Músculo Esquelético/parasitologia , Músculo Esquelético/patologia , Ratos , Triquinelose/tratamento farmacológico , Triquinelose/patologiaRESUMO
The authors propose a mathematical model that makes it possible to estimate the severity of experimental trichinosis from the peripheral blood values of a laboratory animal (white blood cells, neutrophils, eosinophils, and lymphocyates).
Assuntos
Modelos Biológicos , Triquinelose/metabolismo , Triquinelose/fisiopatologia , AnimaisRESUMO
The elastic and photo-elastic characteristics of four laser crystals KY(WO4)2, KGd(WO4)2, KYb(WO4)2, and KLu(WO4)2 are presented. The first pair was reported early, and the last two materials have been investigated for the first time. The full matrix of elastic constants of these monoclinic crystals has been determined. Also, acousto-optical figure of merit for all the basic geometries of isotropic diffraction has been measured. It is proved that potassium rare-earth tungstates has rather good acousto-optical properties and particularly can take place of fused silica in technical applications required high power laser radiation. All the results demonstrate good prospect of these optically bi-axial laser crystals for development of new effective acousto-optical devices.
