RESUMO
The article presents data on the investigation of 15 indices characterizing the interrelation of general changes in the organism with the functional state of neutrophilic polymorphonuclear leukocytes in 866 patients with acute inflammatory diseases of organs of the abdominal cavity and peritonitis and in 203 practically healthy people. A conclusion is made of the expediency of stabilization of the cellular and subcellular membranes, inhibition of activity of proteolytic lysosomal enzymes.
Assuntos
Ensaios Enzimáticos Clínicos , Peritonite/diagnóstico , Permeabilidade da Membrana Celular , Enzimas/sangue , Humanos , Concentração de Íons de Hidrogênio , Lactatos/sangue , Neutrófilos/enzimologia , Peritonite/imunologia , Piruvatos/sangue , Estudos RetrospectivosRESUMO
Separate estimation of intestinal and liver fractions of blood serum alkaline phosphatase in patients with acute forms of impairments corroborated the tissue specificity of these isoenzymes and showed the stable character of alterations in their activity at the initial steps of inflammatory-destructive processes in liver tissue, bile and intestinal tracts. The express methods for estimation of blood serum alkaline phosphatase isoenzymes enabled to carry out the examination within 1.5-2 hrs; the diagnostic methods may be widely used in urgent abdominal surgery.
Assuntos
Abdome Agudo/enzimologia , Fosfatase Alcalina/sangue , Intestinos/enzimologia , Isoenzimas/sangue , Fígado/enzimologia , Humanos , MétodosRESUMO
The activity of the intestinal and hepatic fractions of the serum alkaline phosphatase was studied in 78 patients with acute diseases of organs of the abdominal cavity and in 20 practically healthy people. The character of changes in the activity of the isoenzymes can serve as a reliable evidence of the predominant localization, the degree of the disease and of the inflammatory destructive process, contributes to earlier recognition of acute disease of organs of the abdominal cavity.
Assuntos
Abdome Agudo/diagnóstico , Fosfatase Alcalina/sangue , Ensaios Enzimáticos Clínicos/métodos , Isoenzimas/sangue , Ativação Enzimática , Humanos , Intestinos/enzimologia , Fígado/enzimologiaRESUMO
Operations were performed on 27 patients with perforative gastric tumor. The author believes that resection of the stomach as a planned operation after suturing the tumor is hopeless since the state of the patient within the interval fails to improve while the tumor becomes inoperable. Patients with the fourth stage of the disease in all circumstances have indications for suturing the tumor only.