[No hocus POCUS: high standards should be set for point-of-care ultrasonography]. / Geen hocus POCUS.

Point-of-care ultrasonography (POCUS) was initially limited to simple applications such as diagnosing ascites, sampling pleural fluid and guiding venous access. Use of POCUS is currently on the rise. As radiologists, we endorse the use of ultrasonography as the stethoscope of the future, but we make some critical comments. The interpretation of ultrasonographic findings can have far-reaching therapeutic implications. The patient is therefore entitled to maximum ultrasonographic expertise. Intensive hands-on training starting in early medical school is mandatory and central archiving of ultrasonographic images and reports is essential.

Meta-analysis of the role of colonoscopy after an episode of left-sided acute diverticulitis.

BACKGROUND: Routine colonoscopy was traditionally recommended after acute diverticulitis to exclude coexistent malignancy. Improved CT imaging may make routine colonoscopy less required over time but most guidelines still recommend it. The aim of this review was to assess the role of colonoscopy in patients with CT-proven acute diverticulitis. METHODS: PubMed and Embase were searched for studies reporting the prevalence of advanced colorectal neoplasia (ACN) or colorectal carcinoma in patients who underwent colonoscopy within 1 year after CT-proven left-sided acute diverticulitis. The prevalence was pooled using a random-effects model and, if possible, compared with that among asymptomatic controls. RESULTS: Seventeen studies with 3296 patients were included. The pooled prevalence of ACN was 6·9 (95 per cent c.i. 5·0 to 9·4) per cent and that of colorectal carcinoma was 2·1 (1·5 to 3·1) per cent. Only two studies reported a comparison with asymptomatic controls, showing comparable risks (risk ratio 1·80, 95 per cent c.i. 0·66 to 4·96). In subgroup analysis of patients with uncomplicated acute diverticulitis, the prevalence of colorectal carcinoma was only 0·5 (0·2 to 1·2) per cent. CONCLUSION: Routine colonoscopy may be omitted in patients with uncomplicated diverticulitis if CT imaging is otherwise clear. Patients with complicated disease or ongoing symptoms should undergo colonoscopy.

Image-guided posterior transperineal drainage for presacral abscess: An analysis of 21 patients.

OBJECTIVE: The purpose of this study was to retrospectively evaluate the safety and efficacy of posterior transperineal drainage in patients with presacral abscess. MATERIALS AND METHOD: The records of 21 patients (14 men, 7 women; mean age: 62.1±10 years) who underwent posterior transperineal drainage for the treatment of presacral abscess, either using fluoroscopy or computed tomography guidance, were retrospectively reviewed. Data were analysed with respect to technical success, tolerance, duration of drainage, complications and short-term outcome. RESULTS: A total of 28 posterior transperineal drainage procedures of presacral abscesses were performed in 21 patients, either using fluoroscopy (24/28; 86%) or computed tomography (4/28; 14%) guidance. Technical success rate was 89% (25/28 procedures) and clinical success rate 88% (22/25 technically successful procedures). Transperineal catheter drainage was maintained for 3-105 days (mean 31 days±26 [SD]). After three procedures (3/28; 11%) patients reported discomfort. No major complications were reported. CONCLUSION: This study suggests that posterior transperineal drainage is an effective, safe and well-tolerated procedure for the treatment of presacral abscess.

A systematic review and meta-analysis of outpatient treatment for acute diverticulitis.

BACKGROUND: The shift from routine antibiotics towards omitting antibiotics for uncomplicated acute diverticulitis opens up the possibility for outpatient instead of inpatient treatment, potentially reducing the burden of one of the most common gastrointestinal diseases in the Western world. PURPOSE: Assessing the safety and cost savings of outpatient treatment in acute colonic diverticulitis. METHODS: PubMed and EMBASE were searched for studies on outpatient treatment of colonic diverticulitis, confirmed with computed tomography or ultrasound. Outcomes were readmission rate, need for emergency surgery or percutaneous abscess drainage, and healthcare costs. RESULTS: A total of 19 studies with 2303 outpatient treated patients were included. These studies predominantly excluded patients with comorbidity or immunosuppression, inability to tolerate oral intake, or lack of an adequate social network. The pooled incidence rate of readmission for outpatient treatment was 7% (95%CI 6-9%, I2 48%). Only 0.2% (2/1288) of patients underwent emergency surgery, and 0.2% (2/1082) of patients underwent percutaneous abscess drainage. Only two studies compared readmission rates outpatients that had similar characteristics as a control group of inpatients; 4.5% (3/66) and 6.3% (2/32) readmissions in outpatient groups versus 6.1% (4/66) and 0.0% (0/44) readmissions in inpatient groups (p = 0.619 and p = 0.174, respectively). Average healthcare cost savings for outpatient compared with inpatient treatment ranged between 42 and 82%. CONCLUSION: Outpatient treatment of uncomplicated diverticulitis resulted in low readmission rates and very low rates of complications. Furthermore, healthcare cost savings were substantial. Therefore, outpatient treatment of uncomplicated diverticulitis seems to be a safe option for most patients.

A rare case of Waterhouse- Friderichsen syndrome during primary Varicella zoster infection.

Primary Varicella zoster virus infection in adults is associated with a higher risk of complications when compared with the benign disease course of primary infection during childhood. We present a rare complication of adult primary Varicella zoster in the form of acute, irreversible adrenal insufficiency due to bilateral adrenal haemorrhage, which is also known as the WaterhouseFriderichsensyndrome.

[Treating physicians can perform simple ultrasounds; triage ultrasonography should be reserved for radiologists]. / Behandelend arts kan zelf eenvoudige echo's maken.

We feel that, in trained hands, point-of-care ultrasonography by non-radiologists is of value to patient care. However, more extensive ultrasonography, i.e., triage ultrasonography, requires a skill set and a clinical environment that can currently only be provided by radiologists.

Imaging of patients with clinically suspected appendicitis in the Netherlands: conclusions of a survey.

The aim of this study was to summarize the extent of variation in imaging strategies in patients clinically suspected of having appendicitis. By means of a written survey, the policies for the imaging management of patients clinically suspected of having appendicitis in the Netherlands were inventoried. A questionnaire was sent to the departments of surgery and radiology of all 105 Dutch hospitals, including the 8 academic medical centres, in March 2006. Questionnaires were returned from 98 hospitals. It was found that, in the work-up of patients suspected of having appendicitis, ultrasound or CT was performed in a minority of hospitals for 50% or more of these patients. In the majority of hospitals, it was carried out for less than 50% of these patients. There is a widespread variability in pre-operative imaging regardless of hospital type. This survey shows that, despite the ubiquitous presence of ultrasound and CT in Dutch hospitals, the pre-operative imaging work-up in patients clinically suspected of having acute appendicitis does not reflect this, being performed in only a minority of patients suspected of having acute appendicitis. Radiologists and surgeons alike should be aware of the positive impact of adjunctive imaging in this group of patients - most importantly lowering the negative appendicectomy rate and also lowering total hospital costs.

[Abdominal ultrasound: a task for the radiologist]. / Abdominale echografie: zaak van de radioloog.

In the Netherlands, ultrasound (US) as a primary, symptom-directed diagnostic tool, is used mainly by radiologists and not by internists; there are good reasons for this. It guarantees concentration of expertise in US as well as in CT and MRI, which makes integrated imaging possible. It also guarantees the continuous availability of expertise, optimal digital accessibility, clearly assigns the responsibility, and minimises the radiation risk. Symptom-directed US plays an important role in the triage of patients who are admitted by general practitioners or via the Emergency Ward, and in interdisciplinary and inter-observer assessment. Finally, the lack of self-referral helps to reduce the costs of medical care.

[Acute abdominal pain in the third trimester of pregnancy caused by adnexal torsion based on a small cystic adenoma]. / Acute buik in het derde trimester van de zwangerschap door torsie van het adnexum op basis van een klein cysteadenoom.

A 25-year-old woman presented in the third trimester of pregnancy with severe abdominal pain in the lower right abdominal quadrant. Differential diagnosis included urolithiasis, adnexal torsion and appendicitis. A definitive diagnosis could not be made based on clinical and laboratory examination. Ultrasonography revealed a 3-cm cyst in the lower right abdomen, which was considered unlikely to cause abdominal pain. During laparotomy, adnexal torsion was found, which was deemed to be the cause of the abdominal pain. The twisted portion was uncoiled and the dark-coloured cyst was extirpated. The cyst was determined to be a cystic adenoma. Adnexal torsion is rarely caused by cysts smaller than 5 cm, especially in the third trimester. Emergency laparoscopyllaparotomy should be performed if adnexal torsion is suspected to confirm the diagnosis and uncoil the twist to prevent ovarian damage. Adnexal torsion should be considered in the differential diagnosis of acute abdominal pain in the third trimester of pregnancy.

[Diagnostic policy in patients with a suspected ruptured abdominal aortic aneurysm]. / Diagnostisch beleid bij klinische aanwijzingen voor een geruptureerd aneurysma van de aorta abdominalis.

The clinical diagnosis of a ruptured aortic aneurysm is unreliable, and in haemodynamically stable patients both ultrasound and CT are used to improve diagnostic accuracy. In any patient with a suspected ruptured aneurysm, ultrasound is done upon arrival of the patient in the hospital to confirm or exclude the presence of an aortic aneurysm. If facilities for endovascular reconstruction are available at the hospital, an immediate CT scan with intravenous contrast follows, to find out if and how endovascular treatment should be performed. If endovascular reconstruction is not available, a CT scan without using contrast is carried out. If the CT scan shows a ruptured aneurysm, the patient is transported to the Operating Department without further delay. If the CT scan does not show any signs of rupture, there is time for further investigation. If no alternative condition to explain the patient's symptoms is found, further diagnostic tests such as repeat ultrasound, CT with contrast material and laboratory tests can be performed. If no other serious condition emerges, the aortic aneurysm should be considered symptomatic. In this case, the patient should undergo a rapid, but thorough pre-operative work-up, and go for operation as soon as possible by a rested and experienced operating team as part of the regular day programme.

[Acute abdominal and back pain in a patient with an aortic aneurysm and a duodenum perforation on CT-scan]. / Acute buik- en rugpijn bij een aneurysma van de aorta, en een duodenumperforatie op de CT-scan.

An 82-year old man with a known aneurysm of the abdominal aorta (AAA) presented with a history of acute onset abdominal and back pain of a few hours. He was haemodynamically stable and had pain on pressure over the aneurysm. Ultrasound confirmed the AAA, but could not demonstrate or exclude rupture. Subsequent CT-scan confirmed a non-ruptured AAA and demonstrated a small, curvilinear, hyperdense structure thought to be a fish bone or chicken bone which had perforated the duodenum. On gastroduodenoscopy, a fish bone was found and removed. The patient's symptoms resolved completely within two days. In patients with a possible ruptured AAA, echographic or CT-scan investigations can confirm or exclude the condition thus avoiding unnecessary surgery. These investigations also gather preoperative data for potential endovascular reconstruction. Before the introduction of new visualization techniques a duodenum perforation resulting from the unnoticed swallowing of a sharp object could only be diagnosed by explorative laparotomy. Delay in diagnosis leads to high mortality.

Mesenteric panniculitis: US and CT features.

Mesenteric panniculitis is an aseptic inflammation of mesenteric fat. Before the age of ultrasonography (US) and computed tomography (CT), mesenteric panniculitis was rarely diagnosed, but today the disorder is more commonly encountered, often as an incidental imaging finding. Its exact cause remains unknown. This review illustrates the characteristic US and CT features of mesenteric panniculitis and discusses its differential diagnosis.

[Spontaneous rupture of the bladder]. / Een spontane blaasruptuur.

A spontaneous bladder rupture was diagnosed using ultrasound and CT scan in 3 patients, 1 woman aged 62 and 2 men aged 77 and 42, presenting with abdominal pain, anuria and prior problems with urination. The younger man had suffered from this previously; he was now suffering from bacterial peritonitis due to infected urine. All 3 patients recovered after treatment with a transurethral catheter and antibiotics. A transurethral resection was performed on the benign enlarged prostate of the older man. The combination of non-specific symptoms, the absence of trauma history and its very rare occurrence mean that initially a spontaneous bladder rupture may not be suspected. However, an untreated bladder rupture can lead to life-threatening situations. Screening the abdomen with ultrasound, an ultrasound-guided puncture and CT scan may yield results that suggest a bladder rupture. In most cases, conservative treatment with a transurethral catheter will be sufficient. Sometimes surgical repair of a bladder rupture may be necessary.

Detection of ileocecal Crohn's disease using ultrasound as the primary imaging modality.

At our hospital ultrasound (US) is used as an initial screening procedure in all patients with abdominal symptoms. The purpose of this study was to assess the effect of this policy on the detection of ileocecal Crohn's disease. We retrospectively studied all patients with a new diagnosis of ileocecal Crohn's disease from our institute over the period 1990-2001. The final diagnosis was based on clinical follow-up and pathological, surgical, US, and other radiological findings. We noted who referred the patient to the radiology department, what the initial clinical presumption was, and what the first imaging study was. US diagnoses were determined from the initial US report and US findings were registered from the images. There were a total of 47 patients (20 men, 27 women) with a mean age of 30 years and a median age of 27 years (range 14-75 years). In all patients the initial imaging study was an abdominal US. Using US, a confident diagnosis of ileocecal Crohn's disease was made in 35 of the 47 patients, Crohn's disease was suggested among the differential diagnosis in 10, and an incorrect diagnosis was made in 2 patients. In 28 of 47 patients, the referring physician did not consider Crohn's disease when requesting the initial US examination. In eight patients with appendicitis-like symptoms, the US findings strongly influenced the decision to refrain from operation at that point in time. US, when used as a low-threshold diagnostic procedure, is a reliable and noninvasive means for making an early diagnosis of ileocecal Crohn's disease in patients who present with atypical symptoms. It may prevent both unnecessary therapeutic delay as well as unnecessary surgery.

Effect of ultrasonography and optional computed tomography on the outcome of appendectomy.

The aim of this study was to investigate the value of US and complementary CT in patients with suspected appendicitis, and to detect adverse outcomes of preoperative imaging. We retrospectively reviewed the data of 233 consecutive patients who underwent an appendectomy as an emergency procedure in our hospital, within a 2-year period. Our hospital policy is to perform diagnostic imaging in all patients with clinical suspicion of appendicitis. The US was performed in 227 patients, followed by additional unenhanced helical focused appendiceal CT in 30 patients with equivocal US results. We evaluated the negative appendectomy rate, occurrence of perforation, and our in-hospital delay. Acute appendicitis was pathologically proven in 219 patients, corresponding to a negative appendectomy rate of 6%. The US with optional CT diagnosed appendicitis with a sensitivity of 96.7%. Forty-eight appendices (21.9%) were perforated. The median overall in-hospital delay was 5 h (range 0.5-123.5 h). For the perforated appendices this was 4.5 h (range 0.5-64.5 h), for the non-perforated appendices 6.0 h (range 0.5-123.5 h). In patients with suspected acute appendicitis, US examination with the option of additional CT significantly lowers the negative appendectomy rate as compared with the clinical acumen alone, without adverse effects on the perforation rate or the in-hospital delay.

[Epiploic appendagitis: an underestimated self-limiting acute abdominal condition]. / Appendagitis epiploica: een onderbelichte zelflimiterende acute buikaandoening.

OBJECTIVE: To describe the clinical findings in patients with epiploic appendagitis and to evaluate its natural course. DESIGN: Retrospective. METHOD: A review of the medical records was carried out for all patients who were diagnosed with epiploic appendagitis using ultrasonography and computed tomography (CT), during the period June 1988-October 2001, at the Haaglanden Medical Centre (Westeinde site), The Hague, the Netherlands. RESULTS: The study group consisted of 49 patients, 38 men and 11 women, with a median age of 41 years. The main symptom was focal abdominal pain, with a median diagnostic delay in the patients of 2 days, located in the left lower quadrant (n = 34), right lower quadrant (n = 8), right upper quadrant (n = 6) or left upper quadrant (n = 1) of the abdomen. No other complaints were present with the exception of nausea and vomiting in two patients. Leucocytosis was found in 21% of patients, the erythrocyte sedimentation rate was elevated in 26% of the patients, and signs of peritoneal irritation were found in 53% of the patients. Epiploic appendagitis was correctly included in the clinical differential diagnosis of 2 patients. All of the patients made a complete and uncomplicated recovery under conservative treatment; the majority were symptom-free within 9 days. CONCLUSION: Due to the increased use of diagnostic imaging in patients with acute abdominal symptoms, epiploic appendagitis is much more frequently diagnosed than before. Presenting symptoms of epiploic appendagitis are non-specific, leading to misdiagnosis in most cases. Epiploic appendagitis has a benign natural course and if patients are correctly diagnosed using ultrasonography and CT, unnecessary surgery and medical treatment may be avoided.

Right colonic diverticulitis: MR appearance.

BACKGROUND: We evaluated the magnetic resonance (MR) features of right colonic diverticulitis. METHODS: This prospective study was based on five patients selected from a group of 156 patients admitted to the radiology department for further evaluation because of clinically suspected appendicitis. All five patients had ultrasound (US) and MR studies, and four patients also had computed tomography (CT). RESULTS: In all five patients, right-side diverticulitis was seen as an outpouching of the right colon with associated circumferential wall thickening of the colon and surrounding inflammatory changes. CONCLUSIONS: Our results suggest that MR imaging can be useful in the diagnosis of right colonic diverticulitis. An inflamed diverticulum with adjacent colonic wall thickening and surrounding inflamed fat are characteristic MR signs. MR imaging can be a valuable alternative to CT in young or pregnant patients who have suspected appendicitis and an equivocal US result.