RESUMO
A coaxial dual-camera digital image correlation system using a hypercentric lens was proposed to determine the defect position in the inner wall of a pipeline under loads. Compared with the traditional dual-camera system, this system ensures that both cameras can capture a 360-degree panoramic image in the same position. Herein, the imaging principle of the system was introduced in detail. In addition, the effectiveness and accuracy of the proposed method were verified through verification and application experiments.
RESUMO
OBJECTIVE: To investigate the expression of PTEN in carcinogenesis and development of colon carcinoma and to reveal their correlation with the PI3K/AKT pathway. METHODS: The expressions of PTEN and p-AKT were detected by immunohistochemistry and western blotting in 32 specimens from patients with colon carcinoma. RESULTS: The positive rate of p-PTEN was significantly lower in colon carcinoma (31.25%) than that in normal control tissues (96.87%, P<0.01), and the positive rate of p-AKT was significantly higher in colon carcinoma (87.5%) than that in normal control tissues (15.62%, P<0.01), and expression level of PTEN and p-AKT were related to histological differentiation, distant invasion, lymph node metastasis and Duke's stage (P<0.05). A negative correlation was observed between the expression of PTEN and p-AKT proteins. (r=-0.872, P<0.01). CONCLUSION: The over-expression of AKT accompanied by the loss of PTEN involves carcinogenesis and development of colon carcinoma.
