Clinical diagnosis and treatment and pathological analysis of 52 cases with gastrointestinal stromal tumors / 国际外科学杂志

Objective To investigate clinical manifestations and clinical diagnosis and treatment and pathological and immunohistochemical features in gastrointestinal stromal tumors. Methods The clinical data of fifty-two cases with gastrointestinal stromal tumors were collected, whose clinical diagnosis and treat-ment and pathological features were retrospectively analyzed from January 1995 to December 2007. Results All patients received operation therapy, only forty-five cases with complete surgical resection. The immu-nohistochemical staining showed that the cases with CD117 positive accounted for 100% (52/52) and CD34 positive accounted for 88.5% (46/52). Conclusions Surgery was necessary for all patients, especially complete surgical resection. Gastrointestinal stromal tumors were poor in preoperative diagnosis, which diag-nosis was based on the immunohistochemical staining of the tumor tissue. CD117 and CD34 tumor markers may help to diagnose gastrointestinal stromal tumors.

Laparoscopic-assisted Resection of the Small Intestine for Stromal Tumors:Report of 15 Cases / 中国微创外科杂志

Objective To evaluate the efficacy of laparoscopic-assisted resection of the small bowel for stromal tumors.Methods From January 2003 to May 2007,laparoscopic abdominal exploration was carried out under general anesthesia on 10 patients with space occupying lesion and 5 patients with abdominal pain and hemafecia of unknown origin.After an intestinal lesion was found,a small incision was made at the proper site on the abdominal wall according to the location of the lesion.The diseased intestine was resected outside the abdominal cavity,and then end-to-end anastomosis was performed.Pneumoperitoneum was rebuilt after closing the abdominal cavity in order to observe the blood circulation of the small bowel and intra-abdominal hemorrhage.Results The operation was completed in all the 15 cases.The postoperative pathological examination showed stromal tumors with CD117 positive in 14 cases(93%)and CD34 positive in 9(60%).Three(20%)of the patients were at very low risk,5(33%)at low risk,4(27%)at moderate risk,and 3(20%)at high risk.The mean diameter of the tumors was(2.44?0.63)cm(ranged from 1.5 to 3.6).The operation time was 38 to 72 minutes with a mean of(57.8?10.4),and mean blood loss was(20.1?6.5)ml(10 to 30).The patients were discharged 4 to 7 days after the operation [mean,(5.3?1.1)days],and were followed up for 5 to 36 months [mean,(24.3?8.4)months].No patient had postoperative complications or recurrence in this series.Conclusion Laparoscopy is effective for resection of small bowel stromal tumors.

Effect of glutamine intensified total parenteral nutrition on the postoperative patients with gastrointestinal tract tumour / 临床外科杂志

Objective To investigate the effect of glutamine intensified TPN on nutritional state and immunofunction in the postoperative patients with gastrointestinal tract tumour.Methods 20 patients were divided into two groups including standard TPN group (control group,10 cases) and Glutamine intensified TPN group(study group,10 cases). Period of treatment was 8 days.Immunofunction(IgG,IgM,IgA,C 3,C 4), serum albumin , nitrogen balance were tested.Results (1)The patients serum albumin in the study group was increased significantly as compared with control group (P

Pump-insertion into the left gastric arterial chemoinfusion combined with intraperiponeal chemotherapy in the treatment of advanced stage gastric carcinoma / 中国普通外科杂志

0.05). Nausea, vomiting, alopecia, and bone marrow suppression in the combinedly chemotherapic group were more severe than in the intravenously treated group, but abdominal distension and pain were the major toxic side effect in combinedly chemotherapic group(P