[Clinical effects of tranexamic acid in arthroscope for femoroacetabular impingement].

OBJECTIVE: To evaluate the clinical effects of tranexamic acid in arthroscope for femoroacetabular impingement. METHODS: Totally 34 patients (34 hips) with femoroacetabular impingement underwent hip arthroscopy from June 2016 to December 2018, were randomly divided into two groups named as tranexamic acid group and control group, 17 patients in each group. In TXA group, there were 10 males and 7 females, aged from 20 to 49 years old with an average of (32.1±7.6) years old;15 mg/kg TXA was intravenous drops before operation incision performed at 10 min. In control group, there were 11 males and 6 females, aged from 20 to 49 years old with an average of (30.9±6.2) years old;100 ml normal saline was intravenous drops before operation incision performed at 10 min. Introopertaive and total bloodloss between two groups were compared. Visual analogue scale (VAS) at 3 and 7 days after opertaion were used to evaluate pain relief of hip joint. Modified Harris Hip Score(mHHS) of hip joint at 3, 6, 9 and 12 weeks after oeprtaion were applied to evaluate clinical effects. RESULTS: All patients were obtained follow up over 12 weeks. Incision healed well without infection and deep vein thrombosis. There were no statistical difference in opertaion time bewteen two groups(P>0.05) . Total blood loss and introopertaive blood loss in TXA group were (0.47±0.20) L and (0.18±0.08) L, while (0.66±0.22) L and (0.24±0.01) L in control group;there were statical differences between two groups (P<0.05). There were no dierences in VAS before opertaion and 7 days after opertaion between two groups (P>0.05);VAS at 3 days after opertaion in TXA group was 2.35±1.12 and 3.12±0.70 in control group, and had difference (P< 0.05). There were significance in VAS at 3 and 7 days after opertaion compared with preopertaive between two groups (P< 0.05). Postopertaive mHHS in TXA group at 3 and 6 weeks were 87.72±1.95 and 91.92±2.32, respectively;while 84.08±1.21 and 89.77±3.30 in control group;there were difference between two groups at 3 and 6 weeks after operation (P<0.05);there were no significant difference in mHHS between two groups at 9 and 12 weeks after operation(P>0.05). CONCLUSION: Preoperative application of tranexamic acid could effectively reduce blood loss in arthroscopy for femoroacetabular impingement, thereby improving surgical field of vision, reducing difficulty of surgical operation, which could promote early and rapid rehabilitation of hip function.

[Quantitative characteristics and population dynamics of the endangered plant Thuja koraiensis in Changbai Mountain, China.] / 长白山区濒危植物朝鲜崖柏种群数量特征及动态.

Thuja koraiensis, a second-class nationally protected plant species, is a unique endangered tree species in Changbai Mountain, with important economic and ornamental value. In this study, the age structure, static life table, and survival function of T. koraiensis were established by using individual root diameter and age data based on investigation of wild resources in the main distribution areas of T. koraiensis. The population development trend was predicted by dynamic index and time series analysis. The results showed that the age-class structure of T. koraiensis population was in the shape of "∩", which was a decline type. The survival curve of T. koraiensis population under the dark coniferous forest was the Deevey-3 type, and was Deevey-2 type in pure forest community. Population survival analysis showed that the survival function of T. koraiensis appeared irregular fluctuation under the dark coniferous forest. The population distribution showed dynamic features of sharp drop in early age period, stable in middle age period, and decline in old age pe-riod. In the pure forest community, the dynamic pattern was characterized by the stability in early age period, growth in middle age period, and recession in old age period. Dynamic index and time series analysis showed that the decline rate of dark coniferous forest community was slightly higher than that of pure forest community. Our results showed that T. koraiensis had some recovery ability and that artificial tending should be used to promote its normal regeneration.

Autologous platelet lysates local injections for treatment of tibia non-union with breakage of the nickelclad: a case report.

BACKGROUND: Nonunions of the tibia represent challenging orthopedic problems, which require the surgeon to analyze numerous factors and choose an appropriate treatment. This article presents a case report of tibia and fibula fracture patient who failed the internal fixation surgery and successfully recovered after one course of percutaneous autologous platelet lysates injection. CASE DESCRIPTION: The patient received an internal nickelclad breakage at 9 months post-surgery but reluctant to accept a second surgery, then autologous platelet lysates (APL) injection which is a less invasive method was recommended. The injections were carried once a week for three times. Radiologic evaluation was conducted every month until recovery. DISCUSSION AND EVALUATION: To the best of our knowledge, this is the first reported case of tibia delayed union with breakage of the plate resolved with APL injection. Improved clinical evidence was observed at 4 and 6 months after injection. The patient got good bony union at 8 months post-injection. The patient didn't feel any discomfort postinjection, no complications such as infection, refracture etc. were observed. CONCLUSIONS: APL percutaneous injection could be a new therapeutic option for the treatment of nonunion or delayed healing fractures.