Assuntos
Lipoproteínas/uso terapêutico , Extratos Placentários/uso terapêutico , Vitiligo/tratamento farmacológico , Administração Cutânea , Adolescente , Adulto , Criança , Feminino , Humanos , Raios Infravermelhos/uso terapêutico , Masculino , Pessoa de Meia-Idade , Extratos Placentários/administração & dosagem , Pigmentação da Pele/efeitos dos fármacosRESUMO
Adult T cell leukaemia/lymphoma was first recognised as a clinical entity in southwest Japan. Subsequently the Caribbean has been found to be another area where the disease is endemic, and sporadic cases have been identified in different parts of the world. The human T cell leukaemia/lymphoma virus (HTLV-I) is causally related to adult T cell leukaemia/lymphoma. A subgroup of HTLV, designated HTLV-III, has recently been isolated from many patients with the acquired immunodeficiency syndrome (AIDS) and preAIDS, and there is now evidence that this variant is the primary cause of AIDS. This is the first report from Trinidad to describe 12 cases of adult T cell leukaemia/lymphoma and 14 of AIDS. All were in patients of African descent. No cases were seen in subjects of East Indian descent, who, like those of African descent, comprise as much as 40% of the population. West Indians of African descent may have increased susceptibility to infection with both HTLV-I and HTLV-III.
Assuntos
Síndrome da Imunodeficiência Adquirida/epidemiologia , Leucemia/epidemiologia , Infecções por Retroviridae/epidemiologia , Adulto , Idoso , População Negra , Deltaretrovirus , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Linfócitos T , Trinidad e TobagoRESUMO
A preliminary survey of the incidence of histoplasmosis in the eastern Caribbean was carried out. The percentages of positive histoplasmin skin test reactors in the populations studied were as follows: Barbados (4%), Trinidad (42%) and Guyana (29%). In Trinidad 69% of individuals under 60 had positive test. However a lower proportion (4%) had serological evidence of past infection with Histoplasma capsulatum. The organism was not isolated from the soil although it had been found previously in Trinidad. On this island five previously diagnosed cases of histoplasmosis were identified. The study confirmed the presence of the infection in the area and further investigations are suggested.