RESUMO
INTRODUCTION: The objective of this study is to analyse the appropriateness and characteristics of drug dose calculation for hospitalised, morbidly obese patients. METHODS: Retrospective, descriptive study of dose calculations for drugs prescribed to hospitalised, morbidly obese patients in a tertiary hospital in 2007. The recommendations prepared by the Pharmacy division are used as a standard. RESULTS: We included 62 patients. The mean number of medications prescribed per patient was 12.1 (4-39), and an average of 2.4 (1-10) are listed in the recommendations. A total of 135 drugs were prescribed. Dose calculations for 81 of the above (60 %) coincided with recommendations and 54 (40 %) did not; there were 51 cases of underdosing and three cases of overdosing. DISCUSSION: Improper dosing was detected for prescriptions in the systemic antibiotic and antithrombin drug groups, with underdosing being more common than overdosing.
Assuntos
Cálculos da Dosagem de Medicamento , Obesidade Mórbida/metabolismo , Adulto , Idoso , Analgésicos/administração & dosagem , Antibacterianos/administração & dosagem , Índice de Massa Corporal , Overdose de Drogas , Feminino , Fibrinolíticos/administração & dosagem , Humanos , Pacientes Internados , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Adulto JovemRESUMO
Introducción: El objetivo del trabajo es analizar la adecuación de la dosificación de los fármacos en los pacientes hospitalizados con obesidad mórbida y sus características. Métodos: Estudio retrospectivo y descriptivo de la dosificación de los fármacos prescritos a los pacientes hospitalizados con obesidad mórbida en un hospital de tercer nivel durante el año 2007. Se ha utilizado como estándar las recomendaciones elaboradas por el servicio de farmacia. Resultados: Se incluyó a 62 pacientes. La media de las especialidades farmacéuticas prescritas por paciente fue 12,1 (4-39), y 2,4 (1-10) la de los fármacos incluidos en las recomendaciones, con un total de 135 especialidades prescritas. La dosificación de 81 (60 %) de ellas coincidía con las recomendaciones y 54 (40 %) no; en 51 casos fue por infradosificación y en 3, por sobredosificación. Discusión: Se detecta dosificación inadecuada de los fármacos prescritos de los grupos antibióticos sistémicos y antitrombóticos, con predominio de la infradosificación (AU)
Introduction: The objective of this study is to analyse the appropriateness and characteristics of drug dose calculation for hospitalised, morbidly obese patients. Methods: Retrospective, descriptive study of dose calculations for drugs prescribed to hospitalised, morbidly obese patients in a tertiary hospital in 2007. The recommendations prepared by the Pharmacy division are used as a standard. Results: We included 62 patients. The mean number of medications prescribed per patient was 12.1 (4-39), and an average of 2.4 (1-10) are listed in the recommendations. A total of 135 drugs were prescribed. Dose calculations for 81 of the above (60 %) coincided with recommendations and 54 (40 %) did not; there were 51 cases of underdosing and three cases of overdosing. Discussion: Improper dosing was detected for prescriptions in the systemic antibiotic and antithrombin drug groups, with underdosing being more common than overdosing (AU)
