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1.
World J Transplant ; 14(1): 88938, 2024 Mar 18.
Artigo em Inglês | MEDLINE | ID: mdl-38576750

RESUMO

Hepatic artery thrombosis (HAT) is a devastating vascular complication following liver transplantation, requiring prompt diagnosis and rapid revascularization treatment to prevent graft loss. At present, imaging modalities such as ultrasound, computed tomography, and magnetic resonance play crucial roles in diagnosing HAT. Although imaging techniques have improved sensitivity and specificity for HAT diagnosis, they have limitations that hinder the timely diagnosis of this complication. In this sense, the emergence of artificial intelligence (AI) presents a transformative opportunity to address these diagnostic limitations. The develo pment of machine learning algorithms and deep neural networks has demon strated the potential to enhance the precision diagnosis of liver transplant com plications, enabling quicker and more accurate detection of HAT. This article examines the current landscape of imaging diagnostic techniques for HAT and explores the emerging role of AI in addressing future challenges in the diagnosis of HAT after liver transplant.

2.
Prenat Diagn ; 41(8): 942-948, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33480068

RESUMO

OBJECTIVE: To investigate the role of the interpeduncular angle (IPA) as a new indicator of intracranial hypotension in fetuses with open spinal dysraphism (SD). METHODS: Two groups of fetuses undergoing magnetic resonance imaging (MRI) examination were identified. The study group included fetuses with open SD (n = 21), while the control group included fetuses with a normal brain and spine (n = 43). Two observers retrospectively evaluated axial T2-weighted images of the brain and the IPA was identified and measured. Other features of the Chiari II malformation were also evaluated in the study group and correlated with the IPA. RESULTS: The average value (±SD) of the IPA for the study and control groups was 9.8° ± 18.5° and 60.2° ± 5.9°, respectively. The intergroup analysis of the IPA measurements revealed a statistically significant difference between the groups (p < 0.005). Brainstem slumping or cerebellar tonsillar descent, collapse of the fourth ventricle, and ventriculomegaly also had a significant correlation with a lower IPA (p = 0.001). CONCLUSION: Measuring the IPA may be a useful technique for assessing the degree of intracranial hypotension in fetuses with open SD. This technique can also detect less severe cases of prenatal intracranial hypotension, even before cerebellar tonsillar descent. The lower IPA in fetuses with open SD further supports the theory that cerebrospinal fluid leakage, and not traction, is the underlying cause of Chiari II malformation.


Assuntos
Feto/fisiopatologia , Hipotensão Intracraniana/classificação , Disrafismo Espinal/cirurgia , Adulto , Malformação de Arnold-Chiari/classificação , Malformação de Arnold-Chiari/complicações , Malformação de Arnold-Chiari/cirurgia , Feminino , Feto/cirurgia , Humanos , Imageamento por Ressonância Magnética/métodos , Pessoa de Meia-Idade , Gravidez , Estudos Retrospectivos , Disrafismo Espinal/classificação
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