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1.
Eye (Lond) ; 33(3): 492-504, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30546136

RESUMO

OBJECTIVE: To explore self-inflicted retinal burns from laser pointers in children. METHODS: Literature review of laser pointer retinal injuries in childhood and online survey of UK Consultant Ophthalmologists. A cohort of local children with self-inflicted injury is described. The matter is topical. We review progress in recent legislation and policy change in the UK. RESULTS: Four of 77 case reports of laser burns in childhood analysed reported psychological or behavioural issues. Three of four children in our cohort had such issues. Delay in diagnosis occurred in two of our patients. Structural retinal damage persisted for over 12 months in all four children (seven eyes). Our survey of UK ophthalmologists found 159 cases of injury (85% male), 80% under 20 years of age. The majority of the laser pointers were purchased online. Many patients (36%) suffered moderate vision loss (6/18 to 6/60 Snellen), while 17% (at least 11 patients) suffered severe vision loss (<6/60 Snellen). CONCLUSION: We highlight the risk of macular damage and vision loss from handheld lasers specifically in children with behavioural, learning or mental health issues. The diagnosis may be difficult or delayed in such children. In children with uncertain macular changes, ophthalmologists should explore the history for possible instances of exposure to handheld lasers pointers. Regulatory authorities and manufacturers of handheld lasers need to be aware of the risk to children. Furthermore, there is a need to better inform parents, carers and teachers of the risk of ocular self-injury from such lasers pointers.


Assuntos
Qualidade de Produtos para o Consumidor/legislação & jurisprudência , Queimaduras Oculares/epidemiologia , Lasers/efeitos adversos , Transtornos da Visão/epidemiologia , Criança , Queimaduras Oculares/prevenção & controle , Humanos , Jogos e Brinquedos , Formulação de Políticas , Comportamento Problema , Comportamento Autodestrutivo , Reino Unido/epidemiologia , Transtornos da Visão/prevenção & controle
3.
Neuroophthalmology ; 40(2): 59-68, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27928387

RESUMO

Sarcoidosis can affect the optic nerves by means of optic disc oedema secondary to posterior uveitis, optic disc oedema secondary to raised intracranial pressure, optic neuritis, optic atrophy secondary to compression or infiltration from a primary central nervous system lesion, and primary granuloma of the optic nerve head. The authors report the use of optical coherence tomography in assessing the response to immunosuppression in a 57-year-old woman with an optic nerve head granuloma.

4.
Eye (Lond) ; 30(3): 492-6, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26611842

RESUMO

PURPOSE: There is increasing evidence that high-powered hand-held laser devices cause retinal injury. We present 12-month follow-up data for three patients that we previously reported with such retinal injuries. METHODS: A retrospective case series of three children with maculopathy secondary to exposure to high-power hand-held laser devices. All children underwent clinical examination and spectral domain optical coherence tomography (SD-OCT) at presentation and follow-up. Fundus-controlled microperimetry was also undertaken 12-19 months after exposure. RESULTS: Three children sustained macular injury after exposure to a high-powered hand-held laser. Acutely, they presented with a 'vitelliform-like' maculopathy with reduced vision. Over the course of follow-up, the best corrected Snellen acuity in all three patients improved to 'normal' levels (range 6/6-6/9). Long-term deficits in foveal retinal sensitivity were identified in two patients using fundus-controlled microperimetry. SD-OCT imaging showed persistent disruption of the foveal outer photoreceptor layers in all three children. CONCLUSION: Although visual acuity improved over time, deficits in microperimetry and SD-OCT persisted. All three children had retinal pigment epithelium changes, requiring follow-up for longer-term sequelae of laser injuries such as expansion of retinal atrophy and development of choroidal neovascular membranes.


Assuntos
Lasers/efeitos adversos , Jogos e Brinquedos/lesões , Retina/lesões , Doenças Retinianas/etiologia , Transtornos da Visão/etiologia , Criança , Seguimentos , Humanos , Masculino , Doenças Retinianas/diagnóstico , Doenças Retinianas/fisiopatologia , Estudos Retrospectivos , Tomografia de Coerência Óptica , Transtornos da Visão/diagnóstico , Transtornos da Visão/fisiopatologia , Acuidade Visual/fisiologia , Testes de Campo Visual , Campos Visuais/fisiologia
5.
Eye (Lond) ; 28(2): 231-4, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24434663

RESUMO

PURPOSE: Laser 'toys' can be purchased online and imported with relative ease; the variety of such devices is a potential public safety concern. We describe five children with maculopathy following exposure to laser 'toys'. METHODS: Case series of maculopathy following exposure to laser 'toys'. RESULTS: Five children were seen in our Ophthalmic Unit with macular injuries following exposure to laser 'toys'. Clinically, three children had an acute vitelliform-like maculopathy which resolved to leave sub-foveal retinal pigment epithelium changes with reduced vision. One case was complicated by a choroidal neovascular membrane. CONCLUSION: Laser 'toys', which resemble laser pointers, are increasingly available over the internet. Such 'toys' may not meet safety standards. Retinal injury in childhood following exposure to laser 'toys' is a public safety concern.


Assuntos
Queimaduras Oculares/etiologia , Lasers/efeitos adversos , Jogos e Brinquedos/lesões , Retina/lesões , Adolescente , Criança , Queimaduras Oculares/diagnóstico , Feminino , Angiofluoresceinografia , Humanos , Masculino , Epitélio Pigmentado da Retina/patologia , Acuidade Visual
7.
Orbit ; 23(4): 213-8, 2004 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15590522

RESUMO

PURPOSE: To assess the effect and efficacy of botulinum toxin type A (BTX-A) at reducing and maintaining eyelid synkinesia in aberrant facial nerve regeneration, while concurrently observing for the presence of side effects to differing treatment doses. METHODS: A prospective interventional study of five patients with eyelid synkinesia resulting from aberrant regeneration of the facial nerve. Patients were treated with injections of either 120, 80 or 40 units of BTX-A (Dysport) into the orbicularis oculi. Objective and subjective reduction in synkinesia, maintenance of response and presence of side effects were recorded. RESULTS: All five patients had improvement of the synkinesia with BTX-A treatment. Lower doses were found to be as effective as higher doses. Mean duration of abolished synkinesia was three months. Two patients developed a ptosis which resolved spontaneously. None of the patients treated with the lowest dose of 40 units developed a ptosis. CONCLUSION: Low-dose BTX-A has a lower incidence of ptosis and is effective in the treatment of aberrant facial nerve regeneration.


Assuntos
Blefarospasmo/tratamento farmacológico , Toxinas Botulínicas Tipo A/uso terapêutico , Nervo Facial/anormalidades , Regeneração Nervosa , Fármacos Neuromusculares/uso terapêutico , Sincinesia/tratamento farmacológico , Adulto , Idoso , Blefarospasmo/etiologia , Músculos Faciais/inervação , Feminino , Humanos , Masculino , Sincinesia/etiologia
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