Metástasis bilateral en conducto auditivo interno de melanoma maligno / Bilateral metastasis in the internal auditory canal of malignant melanoma

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Radioterapia como tratamiento paliativo de la obstrucción biliar tumoral / Radiotherapy as palliative treatment of malignant biliary obstruction

OBJETIVOS: La ictericia obstructiva es un síntoma frecuente en los tumores irresecables de la vía biliar. Presentamos un caso clínico con diagnóstico de colangiocarcinoma recurrente con ictericia obstructiva tratada con radioterapia externa. Caso clínico: Paciente con diagnóstico de colangiocarcinoma recurrente metastásico que a pesar de la colocación de dos endoprótesis biliares continúa con ictericia y mal estado general. Se decide tratamiento con radioterapia externa paliativa sobre la lesión tumoral que comprime la vía biliar administrando una dosis total de 20Gy en 5 fracciones de 400 cGy. Tras la finalización del tratamiento las cifras de bilirrubina se estabilizan y comienzan a descender de forma progresiva hasta niveles normales, resolviéndose la ictericia y mejorando la calidad de vida del paciente. CONCLUSIONES: La radioterapia externa puede ser un tratamiento paliativo efectivo para descomprimir la vía biliar y mejorar la sintomatología en pacientes con tumores irresecables

OBJECTIVES: Obstructive jaundice is a frequent symptom in unresectable tumours of the bile duct. The case is reported of a patient diagnosed with recurrent cholangiocarcinoma with obstructive jaundice treated with external radiotherapy. Clinical case: A 47 year- old male diagnosed with recurrent and metastatic cholangiocarcinoma. Despite placing two biliary stents, the patient continued have high bilirubin levels, jaundice and a poor condition overall. With these findings, the proposed treatment was palliative external radiotherapy over the tumour lesion that compressed the bile duct, with a total dose of 20Gy in 5 fractions of 400 cGy. After completing the treatment, the bilirubin values began to descend gradually to normal levels, the jaundice disappeared and the quality of life of the patient improved. CONCLUSIONS: External radiotherapy can be an effective palliative treatment to decompress the bile duct and improve the symptoms in patients with unresectable tumours

Indicaciones de la tomografía por emisión de positrones y la gammagrafía ósea en la estadificación del cáncer de pulmón / Indications for positron emission tomography and bone gammagraphy in staging lung cancer

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Radio-induced bullous pemphigoid.

We report on the appearance of two new cases of radio-induced bullous pemphigoid (BP), a rare complication of radiotherapy. Both were elderly women, were treated for breast cancer and suffered (BP) during the irradiation, the evolution was favorable with steroid therapy.

Extrapulmonary small cell carcinoma in breast and prostate.

Extrapulmonary small cell carcinoma in breast and prostate are uncommon neoplasms. In the literature most of the data come from case reports and these show that these tumours are highly aggressive. Histologically, they bear striking similarities to small cell carcinomas of the lung and usually show evidence of additional histologies. Treatment, which may include surgery, radiotherapy and chemotherapy, is based on the clinical stage. We present the evolution of two cases.