[Broncho-Vax and IRS 19 in the treatment of recurrent respiratory tract inflammation in children]. / Broncho-Vaxom a IRS 19 v liecbe recidivujúcich zápalov dýchacich ciest u deti.

A group of 80 children with relapsing infections of the respiratory pathways (a minimum of three during the previous period) were investigated during the first year of the investigation (1987-88) with regard to the number and duration of the disease, absence from school, antibiotic consumption and use of bronchodilatating agents. In the subsequent year 1988-1989 the children were divided into a group treated with Broncho-Vaxom, a group treated with IRS 19 and a control group. Before the onset of administration and then every two months functional examinations of the lungs were made in the children. At the beginning of treatment and after its termination some immunological and laboratory values were examined. The effect of treatment was evaluated also subjectively by the parents and physician. Both preparations had a favourable effect on prevention of relapses of respiratory infections. This effects was more favourable after Broncho-Vaxom, in particular in prevention of inflammations of the lower respiratory pathways. IRS 19 eliminates relapses of infections of the upper respiratory pathways sooner.

[Carbocysteine in the treatment of recurrent bronchitis in infants]. / Karbocystein v liecbe recidivujúcich bronchitíd u dojciat.

In a group of 51 children aged 6-24 months the therapeutic effectiveness of the mucolytic preparation carbocysteine was tested and compared with the effect of Ipeca syrup. The effect was evaluated by means of a point score comprising changes of the clinical picture of the disease and the use of other laboratory examinations. The results of the examination revealed the more favourable effect of carbocysteine, as compared with a mixture of Ipeca syrup in the treatment of acute relapsing bronchitis in infants.

[Disorders of the cardiovascular system in congenital lentiginosis]. / Poruchy kardiovaskulárneho systému pri vrodenej lentiginóze.

The authors investigated during the last 10 years four patients with lentiginosis and affection of the heart. In none of them the symptoms were complete enough to include it under the leopard syndrome. In two patients the authors found changes in the outflow portion of the right ventricle which was in their opinion caused by hypertrophy of the interventricular septum and musculature of the right ventricle. The authors consider the term lentiginocardiomyopathic syndrome suitable for this rare clinical and genetic entity. The authors check patients with lentiginocardiomyopathic syndrome regularly after 6-month intervals. In two children they recorded progression of the heart disease.