Lipid profile in women receiving depot medroxyprogesteron acetate as contraceptive.

The study was conducted to estimate the serum lipid levels in women using depot medroxyprogesterone acetate (DMPA). A total of 90 Bangladeshi married women of age group 15-40 years attending the Model Family Planning Clinic, Mymensingh Medical College Hospital, Mymensingh, from July 2010 to June 2011. Patients were classified into three groups comprising those using the drug for 3 months (n=30), 1 year (n=30), and 2 years (n=30), respectively, compared to a control group (n=30) of married non-hormonally treated women of similar ages. Their age, weight, height, BP and BMI were recorded; all the subjects were clinically examined. Blood samples were collected for biochemical assay of serum lipid profiling parameters, such as total cholesterol, HDL-C, TAG and LDL-C. Data were collected and processed according to the design and objectives of the study. A significant (p<0.01) decrease in serum total cholesterol was observed up to 1 year of using DMPA, but a sharp increase was observed in 2 years group. Likewise total cholesterol, HDL-C was significantly (p<0.01) decreased in the 1 year group and rapidly increased in the 2 years group. A significant (p<0.01) reduction in TAG level was observed throughout the study tenure when compared with control group. No significant (p>0.05) difference in LDL-C level was observed among the treatment groups. The study concludes that DMPA induced significant alterations in lipid profiling parameters of the studied population and prolong use does not have risk of atherosclerosis; however, further study with a larger sample size is suggested for a general recommendation.

Serum calcium level among normal pregnant and pre-eclamptic women in a sub urban area of Bangladesh.

Pre-eclampsia along with its complications seems to be one of the major causes of maternal morbidity and mortality. Despite numerous studies, the etiology of pre-eclampsia has not yet been fully elucidated. The present study prospectively determines and evaluate whether maternal serum levels of calcium has any association with pre-eclampsia. It was a cross sectional study carried out in the department of Biochemistry, Mymensingh Medical College from July 2009 to June 2010. A total of 76 subjects were selected with the duration of pregnancy from 28th wks to term. Among them 42 were normal pregnant women and 32 were pre-eclamptic, admitted in the department of obstetrics and gynaecology Mymensingh Medical College Hospital. The mean±SD serum calcium of normal pregnant women and that of the pre-eclamptic were 7.62±0.24 and 7.32±0.28mg/dl respectively. There was significant (p<0.001) decrease in serum calcium in subject with pre-eclampsia in comparison to that of the normal pregnancy. So, level of calcium may be significantly decreased in pre-eclampsia.

Morphometric study of thyroid angle in different age and sex in Bangladeshi cadaver.

This cross sectional descriptive study was to measure the thyroid angle and to establish the difference between sexes of different age groups in Bangladeshi cadaver. A total 60 human larynges were collected by purposive sampling from October 2008 to March 2009. Among them 45(male 23 and female 22) were collected from Bangladeshi cadavers (9 to 60 years) at the autopsy laboratory of Department of Forensic Medicine and 15 (male 6 and female 9) from stillborn infants of viable age (28 to 40 weeks of gestation) from Gynaecology and Obstetrics Department of Mymensingh Medical College, Mymensingh. The thyroid angle was measured and significant differences of the dimensions between different age and sex groups were observed. In the present study observed findings was compared with those of other researchers. The mean±SD thyroid angle was found as 65.00±11.65 degree in age Group A (28 to 40 weeks of gestation), 73.69±6.56 degree in age Group B (9 to 16 years) and 77.76±7.76 degree in age Group C (17 to 60 years). The mean thyroid angle was higher in female (83.1667±5.78220 degree) than that in male (73.9412±7.09460 degree) and statistically moderately significant in Group C, where t = 3.853 and p = 0.001. In statistical analysis, differences between age and sex groups were calculated by using Students (unpaired) 't' test. The present study revealed that the value was significantly greater in adult female than male and the value increased with age.