RESUMO
The aim of this research was to fabricate a burn dressing in the form of hydrogel films constructed with cellulose nanofibers (CNF) that has pain-relieving properties, in addition to wound healing. In this study, the hydrogels were prepared in the form of film. For this, CNF at weight ratios of 1, 2, and 3 wt.%, 1 wt.% of hydroxyethyl cellulose (HEC), and citric acid (CA) crosslinker with 10 and 20 wt.% were used. FE-SEM analysis showed that the structure of the CNF was preserved after hydrogel preparation. Cationization of CNF by C6H14NOCl was confirmed by FTIR spectroscopy. The drug release analysis results showed a linear relationship between the amount of absorption and the concentration of the drug. The MTT test (assay protocol for cell viability and proliferation) showed the high effectiveness of cationization of CNF and confirmed the non-toxicity of the resulting hydrogels.
RESUMO
Nanofilters made with high adsorption freeze-dried modified cellulose nanofiber (CNF) aerogel were produced. The modification was made using functional groups containing phthalimide, and then their ability to adsorb particulate matter (PM) was evaluated and compared with the control filter (HEPA). The results showed that the highest adsorption of PM2.5 (99.95%) belonged to the nanofilters made of 1.5% phthalimide-modified CNF aerogel, and the lowest adsorption (76.66%) was related to the control samples. Moreover, based on the results, the nanofilter produced from freeze-dried phthalimide-modified CNF aerogel showed high filtration efficiency as well as excellent resistance to temperature and humidity. This modification enables the filter to operate in different environmental conditions, especially for particles less than 0.1 µm that are mainly responsible for reducing air quality, human health, air visibility, and climate change. In conclusion, we developed an environmentally friendly biodegradable nanofilter capable of high-performance filtration functions and structural stability in different environmental conditions.
