[Evaluation of the function of the left heart ventricle during the modeling of right ventricular hyperfunction using a pulsatile pump]. / Otsenka funktsii levogo zheludochka serdtsa pri modelirovanii pravozheludochkovoi giperfunktsii s pomoshch'iu pul'siruiushchego nasosa.

Left ventricular function was studied in 11 acute experiments on dogs during right ventricular hyperfunction modelling using an artificial heart ventricle (AHV). The right ventricle was excluded from circulation and replaced by AHV. First the baseline condition with regard to the cardiac index was recovered. The right ventricle was considered to be completely functionally replaced when no hemodynamic changes were observed. When the AHV output increased by 26% there were no considerable changes in hemodynamics and the functional condition of the left ventricle remained adequate. If the output was 56% higher certain hemodynamic changes and a tendency towards deterioration of the left ventricular function have been observed. The final stage of the experiments was characterized by twice as high ANV output, as compared to the initial one, which caused considerable hemodynamic changes and greater left ventricular weakness.

[Choice of treatment methods in initial forms of ischemic heart disease]. / Vybor metodov lecheniia pri nachal'nykh formakh ishemicheskoi bolezniserdtsa.

The authors examined 125 patients with initial forms of ischemic heart disease (duration of no more than 2 months). The examination comprised coronarography, ventriculography, 24-hour ECG monitoring, and bicycle ergometry. The patients were divided into two groups: group 1 consisted of 81 patients who received nonoperative treatment; group 2 was formed of 44 patients who underwent operation for aortocoronary shunting. The results of treatment were appraised according to three parameters: a state of angina pectoris, prevention of myocardial infarction, and survival. They were studied in the hospital stage and in the long-term follow-up periods. Comparative analysis showed that surgery had some advantages over nonoperative treatment in relieving completely attacks of angina pectoris and transitory episodes of myocardial hypoxia. Patients who had been operated on possessed higher tolerance to physical exertion. None of the two methods of treatment had advantages over the other in regards to prevention of myocardial infarction, a fatal outcome, and prolongation of survival.

[Surgical treatment of patients with ischemic heart disease associated with the lesions of the brachiocephalic arteries]. / Khirurgicheskoe lechenie bol'nykh ishemicheskoi bolezn'iu serdtsa s sochetannym porazheniem brakhitsefal'nykh arterii.

Experience with the detection and surgical treatment of combined lesions of brachiocephalic arteries in coronary patients is reported. Noninvasive screening of 500 coronary patients detected brachiocephalic arterial lesions with transitory ischemic attacks or without cerebral ischemic symptoms in 82 patients. Simultaneous reconstructions are recommended for severe lesions of the main cerebral vessels and coronary arteries, and two-step operations, with cerebral flow recovery as the priority, for cases of mild clinical anginal manifestations. Forty-one operations were performed, 18 of them being simultaneous. One (2.4%) patient died. Cerebral and coronary symptoms were largely improved in discharged patients.

[Clinical and functional results of aortocoronary shunting in patients with ischemic heart disease]. / Kliniko-funktsional'nye rezul'taty aortokoronarnogo shuntirovaniia u bol'nykh ishemicheskoi bolezn'iu serdtsa.

Survival rates were evaluated in 3 groups of patients: those with an isolated lesion of the anterior interventricular branch of the left coronary artery (group 1), multiple coronary arterial lesions (group 2) and a more than 50% narrowing of the left coronary-arterial trunk (group 3) following autovenous aortocoronary shunting of 1 to 5 coronary arteries. Drug-treated patients with similar coronary arterial lesions and clinical manifestations were taken as controls. Long-term survival rates of surgical patients were significantly higher, as compared to those of medication-treated patients in groups 2 and 3. There was no significant difference in survival rates of first-group patients. Long-term survival was dependent on the scope of revascularization and pretreatment myocardial contractility.

[Comparative evaluation of the results of conservative and surgical treatment of unstable angina at long-term follow-up]. / Sravnitel'naia otsenka rezul'tatov konservativnogo i khirurgicheskogo lecheniia nestabil'noi stenokardii v otdalennye sroki nabliudeniia.

Two hundred patients with unstable angina were examined. Of those, 100 were on medication only, while another 100 had undergone aortocoronary shunting. Five-year survival rate was higher, and the quality of life was better, in the surgical patients, as compared to conservative cases.