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Mil Med ; 182(7): e1969-e1972, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28811000

RESUMO

Cutaneous leishmaniasis typically presents as a painless papule progressing to an ulcer or plaque. In this case study of the ear, the disease manifested as a small painful bump progressing into redness and swelling about the ear with purulent drainage. After multiple oral/intravenous antipseudomonal, antistaphylococcal, and antifungal treatments, there was no improvement. The skin progressed to an erythematous plaque and hemorrhagic ulcer; punch biopsy and speciation revealed Leishmaniasis guyanensis. The patient was switched to a seven-dose course of intravenous L-amphotericin B (visceral leishmaniasis protocol). Within 21 days, pain and edema resolved and the ulcers healed. Three-month follow-up demonstrated no recurrence. Further studies are needed to evaluate the use of L-amphotericin B in Leishmaniasis guyanensis.


Assuntos
Orelha/parasitologia , Leishmaniose Cutânea/diagnóstico , Adulto , Anfotericina B/farmacologia , Anfotericina B/uso terapêutico , Antiprotozoários/farmacologia , Antiprotozoários/uso terapêutico , Orelha/lesões , Guiana , Perda Auditiva/etiologia , Humanos , Leishmania guyanensis/patogenicidade , Masculino , Otite Externa/diagnóstico , Otite Externa/fisiopatologia , Viagem
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