[The character of dyslipidemia and myocardial and carotid arterial remodeling in young patients with essential hypertension].

The purpose of the investigation was to study the character of myocardial and vascular revascularization by the example of the carotid artery (CA) in young patients with arterial hypertension in correlation with biochemical and clinical data. Sixty-eight patients were examined. EchoCG and sonography were performed using SONOS 4500 device. Left ventricular myocardial mass (LVMM) was calculated using R. Devereus formula. Intimomedial thickness (IMT) was measured in the ostium of the common CA (CCA) bifurcation. Lipidogram was performed by "dry chemistry" method using Reflotron bioanalyzer. An elevated LVMM index was revealed in 65% of the subjects. Concentric left ventricular (LV) hypertrophy prevailed over other types of myocardial remodeling (53%). LV diastolic dysfunction was found in 23% of the patients; LV systolic dysfunction was revealed in 56% of the subjects. IMT was increased in 27% of cases, C- and S-shape curvatures were revealed in 56.6% of the patients. In 31.3% of the subjects, atherosclerotic plaques with a 20% to 50% stenosis were found. Various forms of dyslipidemia were revealed in 75.6% of the patients. In conclusion, dyslipidemia and lesion of target organs in a form of myocardial and vascular remodeling require active antihypertensive and hypolipidemic therapy to prevent complications.

[Epidemiologic and social aspects of arterial hypertension in subjects of young age (according to the data of examination of organized groups of employees in Smolensk]. / Epidemiologicheskie i sotsial'nye aspekty arterial'noi gipertonii u lits molodogo vozrasta (po rezul'tatam obsledovaniia organizovannogo trudovogo kollektiva Smolenska).

AIM: To study prevalence of arterial hypertension (AH) in young Smolensk population sample, AH risk factors, awareness of the patients about their disease, treatment compliance. MATERIAL AND METHODS: The in-office study covered 1068 employees. In diagnosis of AH, the patient answered the questions about AH risk factors, attitude to treatment. RESULTS: All was highly prevalent in the examined population (27.9%). Patients under 45 years of age accounted for 38.9% of all the examinees with AH. The risk factors included overweight and obesity (65.5%), smoking (53.5%), family AH history (52.6%). In spite of high awareness about AH (72.4%) and opinion about AH as an important social problem, young patients demonstrate low treatment compliance (12%). This is explained by psychological features of such patients. CONCLUSION: It is necessary to examine quality of life of AH patients aged under 45 years, setting up of special schools to maintain educational activity, psychological and rehabilitation care.