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1.
PLoS One ; 19(3): e0296864, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38536833

RESUMO

The modeling of uncertain information is an open problem in ontology research and is a theoretical obstacle to creating a truly semantic web. Currently, ontologies often do not model uncertainty, so stochastic subject matter must either be normalized or rejected entirely. Because uncertainty is omnipresent in the real world, knowledge engineers are often faced with the dilemma of performing prohibitively labor-intensive research or running the risk of rejecting correct information and accepting incorrect information. It would be preferable if ontologies could explicitly model real-world uncertainty and incorporate it into reasoning. We present an ontology framework which is based on a seamless synthesis of description logic and probabilistic semantics. This synthesis is powered by a link between ontology assertions and random variables that allows for automated construction of a probability distribution suitable for inferencing. Furthermore, our approach defines how to represent stochastic, uncertain, or incomplete subject matter. Additionally, this paper describes how to fuse multiple conflicting ontologies into a single knowledge base that can be reasoned with using the methods of both description logic and probabilistic inferencing. This is accomplished by using probabilistic semantics to resolve conflicts between assertions, eliminating the need to delete potentially valid knowledge and perform consistency checks. In our framework, emergent inferences can be made from a fused ontology that were not present in any of the individual ontologies, producing novel insights in a given domain.


Assuntos
Ontologias Biológicas , Semântica , Incerteza , Teorema de Bayes , Bases de Conhecimento , Lógica
2.
Methods ; 202: 110-116, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-34245871

RESUMO

This paper presents a heart murmur detection and multi-class classification approach via machine learning. We extracted heart sound and murmur features that are of diagnostic importance and developed additional 16 features that are not perceivable by human ears but are valuable to improve murmur classification accuracy. We examined and compared the classification performance of supervised machine learning with k-nearest neighbor (KNN) and support vector machine (SVM) algorithms. We put together a test repertoire having more than 450 heart sound and murmur episodes to evaluate the performance of murmur classification using cross-validation of 80-20 and 90-10 splits. As clearly demonstrated in our evaluation, the specific set of features chosen in our study resulted in accurate classification consistently exceeding 90% for both classifiers.


Assuntos
Sopros Cardíacos , Ruídos Cardíacos , Algoritmos , Sopros Cardíacos/diagnóstico , Humanos , Aprendizado de Máquina , Máquina de Vetores de Suporte
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