The Effect of Maternal Adverse Childhood Experiences (ACEs) on Substance Use During Pregnancy.

OBJECTIVES: To analyze adverse childhood experiences (ACEs) among mothers of newborns referred to a hospital's child protection team (CPT) for suspected substance exposure. Researchers hypothesized that a higher prevalence of these mothers have ≥ 4 ACEs than female counterparts in the general population. The study team also explored whether associations existed between type of maternal ACEs and substance use in pregnancy. METHODS: Retrospective review of infant referrals to the CPT in the 3 years after adding an ACEs questionnaire to the consultation process. Bivariate analyses and multivariate logistic regression models examined associations between prenatal substance use and maternal ACEs prevalence, controlling for demographics. RESULTS: Data from 222 infants (four sets of twins) and 218 mothers were analyzed. Half (50.0%) the infants had withdrawal symptoms. Most (67.0%) women had positive toxicology screens, while 85.0% reported prenatal substance use. Half (50.9%) the mothers reported ≥ 4 ACEs and these individuals had significantly higher odds of cannabinoid use [adjusted odds ratio (aOR), 3.7; 95%CI 2.0, 6.9, p < 0.001) than those with < 4 ACEs. A significant association was found between substance use and ACEs in the household challenges category (p = 0.03), especially parental separation/divorce (p < 0.001). CONCLUSIONS FOR PRACTICE: As hypothesized, a higher prevalence of mothers referred to the CPT had ≥ 4 ACEs than women in the general population (50.9% vs. 15.2%), and a large proportion had used substances while pregnant. Routine prenatal ACEs screening and universal, nonpunitive toxicology testing of infants and mothers at birth may provide opportunities for intervention while reducing the transgenerational impact of ACEs.

It is known that Adverse Childhood Experiences (ACEs) put people at risk of poor health choices and outcomes later in life. Pregnant people who have experienced ACEs­especially those with ≥ 4 events ­are at risk for prenatal substance use, exposing their infants in utero. The high prevalence of people in this study with ≥ 4 ACEs whose infants tested positive for substance exposure provides further evidence of the association between ACEs and substance use in pregnancy. Prenatal screening for childhood adversity may identify people at risk and provide opportunities for intervention, thus reducing the transgenerational impact of ACEs.

Calibration Tool to Standardize Magnification during Smartphone-based Microsurgical Skills Training.

Acquiring microsurgical skills outside the operating room has traditionally required not only a substantial amount of time and practice, but also a significant amount of equipment, such as an operating microscope. Difficulty in accessing such equipment hinders opportunities to acquire skills, particularly in environments with limited resources. Furthermore, the current era of restricted work hours has led to an increased demand for surgical skills training outside of the clinical setting. The near-ubiquity of the standard smartphone and its ability to magnify, illuminate, and record videos give it the potential to serve as an excellent tool to conduct training in microsurgical skills-particularly in the context of self-directed, home-based training. However, the variety of smartphones available and their inherent variability in technical and optical specifications have made it difficult to create a standardized, reproducible, and interchangeable system for smartphone-based microsurgical training. Therefore, we have developed a simple and effective calibration tool that ensures accurate magnification levels so that smartphone-based microsurgical training can be performed reliably with any device and in virtually any surroundings.