Air pollution dispersion in Hail city: Climate and urban topography impact.

Due to the rapid urbanization of many cities around the world, industrial manufacturing plants have been expanded quickly, leading to the discharge of large amounts of pollutants into the environment. Consequently, a significant deterioration in local air quality is recorded, representing a high health risk for the city's residents. In this context, the main objective of this work is to understand the dispersion of gas pollution in high-density urban environments, specifically the Hail region of Saudi Arabia. The simulations carried out with Ansys Fluent 19.0 were based on actual climatic conditions, with particular attention paid to accurately reproducing the exact topography of the study area. The main results concern the characterization of flow behavior and the dispersion of gas pollutants emitted by power plants. Several factors, including building geometry and wind speed, are examined. The study reveals that for a reference wind speed of more than 7 m/s, gaseous pollution exhibits a significant tendency to accumulate within buildings, resulting in significant concentrations.

Biodegradable Magnetic Molecularly Imprinted Anticancer Drug Carrier for the Targeted Delivery of Docetaxel.

Molecularly imprinted biodegradable polymers are receiving considerable attention in drug delivery due to their ability of targeted recognition and biocompatibility. This study reports the synthesis of a novel fluorescence-active magnetic molecularly imprinted drug carrier (MIDC) using a glucose-based biodegradable cross-linking agent for the delivery of anticancer drug docetaxel. The magnetic molecularly imprinted polymer (MMIP) was characterized through scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction spectroscopy, and vibrating sample magnetometry (VSM). The MMIP presented a magnetization value of 0.0059 emu g-1 and binding capacity of 72 mg g-1 with docetaxel. In vitro and in vivo studies were performed to observe the effectiveness of the MIDC for drug delivery. The cell viability assay suggested that the MMIP did not present toxic effects on healthy cells. The magnetic property of the MMIP allowed quick identification of the drug carrier at the target site by applying the external magnetic field to mice (after 20 min of loading) and taking X-ray images. The novel MMIP-based drug carrier could thus deliver the drug at the target site without affecting the healthy cells.