1.
J Pharm Belg
; 45(3): 219-23, 1990.
Artigo
em Francês
| MEDLINE
| ID: mdl-2205718
RESUMO
The optimisation of the PAF antagonistic activity of RP 48740 led to the discovery of still more potent molecules of the pyrrolo[1,2-c]thiazole family: RP 52629, RP 52770 and RP 59227. The latter compound, for which a stereo-specific synthesis was developed, exhibits a very high potency as a PAF receptor antagonist.