RESUMO
The use of cannabis for recreational as well as medicinal use is on the rise recently with more states legalizing it. We conducted a review analysis of the literature published on acute respiratory failure from vaping cannabis oil. We have also summarized the clinical details (age, length of stay, mode of ventilation, common clinical findings, and steroid use) along with common laboratory abnormalities. This article aims to educate health care providers on the clinical manifestations and management strategies for vaping-induced acute respiratory failure. We also discussed the different available formulations of cannabis oil and key ingredients responsible for the vaping-associated lung injury.
Assuntos
Lesão Pulmonar Aguda/etiologia , Cannabis/efeitos adversos , Óleos de Plantas/efeitos adversos , Vaping/efeitos adversos , Adulto , Sistemas Eletrônicos de Liberação de Nicotina , Feminino , Humanos , Inalação , Masculino , Tomografia Computadorizada por Raios X , Adulto JovemRESUMO
Nocardia causes rare opportunistic infections, that can be challenging to diagnose because of atypical features on conventional microbiological identification techniques. Immunosuppressed patients are more susceptible to infections from Nocardia and are associated with multi-organ involvement. We report a case of a 63-year-old male who developed peritonitis from Nocardia farcinica that rarely causes infections in humans. The nonspecific symptoms, negative blood cultures, and slow growth can make diagnosis difficult. Despite aggressive therapy, the virulence and inherent resistance to the antibiotics can result in high mortality from Nocardia farcinica infections.
Assuntos
Antibacterianos/uso terapêutico , Nocardiose/microbiologia , Nocardia/isolamento & purificação , Peritonite/microbiologia , Farmacorresistência Bacteriana , Evolução Fatal , Humanos , Hospedeiro Imunocomprometido , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Nocardia/crescimento & desenvolvimento , Nocardiose/diagnóstico , Nocardiose/tratamento farmacológico , Diálise Peritoneal/efeitos adversos , Peritonite/tratamento farmacológicoRESUMO
An 8-month-old infant with cyanotic heart disease and transfusion-associated Babesia microti infection is reported here. At initial presentation, she was ill appearing, febrile and cyanotic. Laboratory tests revealed severe anemia, thrombocytopenia and an increase in hepatic enzymes. The diagnosis was made by the presence of intraerythrocytic parasites on thin blood smear and confirmed by serology and polymerase chain reaction. The infant was treated successfully with a combination of oral azithromycin and atovaquone. This combination is an alternative to clindamycin and quinine for the treatment of children with babesiosis.