[Anti-inflammatory activity of domestic papain]. / Izuchenie protivospalitel'noi aktivnosti otechestvennogo papaina.

The influence of domestic papain to the course of experimental inflammation due to formalin, dextrane, histamine, serotonin and infectious arthritis has been studied. The domestic papain in doses of 0.325 and 0.75 mg/kg possesses strongly marked antiinflammatory activity and this ability is no less than that of butadion and indomethacin.

[Pharmacological study of papain from the papaya plant cultivated in Uzbekistan]. / Farmakologicheskoe issledovanie papaina rasteniia papaiia, kul'tivirovannogo v Uzbekistane.

It was experimentally established that papain from papaya cultivated in Uzbekistan possesses a pronounced proteolytic activity: 0.1, 0.5, and 1% papain solutions decreased the weight of burn crust in vitro and accelerated experimental burn healing in vivo. Under clinical conditions, papain produced therapeutic effect in patients with inflammatory disorders in genitals, intestine, liver, and eye. The pharmacological effects of papain produced from Uzbek papaya are identical to those of the commercial product from Merck.