[Practical significance of middle molecules of the blood in assessing the severity of the status of neurosurgical patients]. / Prikladnoe znachenie srednikh molekul krovi dlia otsenki tiazhesti sostonianiia neirokhirugicheskikh bol'nykh.

Study of the content of medium-size molecules (MM), residual nitrogen, creatinine, and urea in the blood of 80 neurosurgical patients with various diseases showed correlation between the severity of the patient's general condition and the MM level. No correlation was noted between the content of MM, creatinine, and urea. The MM level in the blood correlated with that of residual nitrogen in 20% of cases. The MM dynamics may serve as a prognostic sign of the course and outcome of the disease. The MM content corresponds to the severity of the patient's general condition and is not dependent on the etiological and pathogenetic factors.

[Elastic properties of the cerebrospinal system and cerebrospinal fluid dynamics in intracranial hypertension and normotensive hydrocephalus in adults]. / Elasticheskie svoistva tserebrospinal'noi sistemy i likvorodinamika pri vnutricherepnoi gipertenzii i normotenzivnoi gidrotsefalii u vzroslykh.

Time course of changes of the CSF and the elastic properties of the cerebrospinal system were studied in 25 patients with normotensive hydrocephalus and in 26 patients suffering from benign intracranial hypertension. In 66% of cases with the normotensive hydrocephalus syndrome and in 60% of those with benign intracranial hypertension CSF resorption resistance and the elasticity gradient increased. Shunting operations proved effective in such cases.

[Tryptophan loading and its plasma concentration in neurosurgical patients]. / Nagruzka triptofanom i ego soderzhanie v plazme krovi u neirokhirurgicheskikh bol'nykh.

Tests for blood plasma tryptophan in patients with various diseases of the nervous system showed a statistically significant increase of its content in tumors of the astrocytic series in patients with meningiomas and oligodendrogliomas. The character of the tryptophan excretion curve after a load in neurooncological patients was different from that in healthy individuals and patients with thrombosis of the sinus and arachnoencephalitis. Hydrocortisone injection normalized the tryptophan curve in patients and, consequently, also the tryptophanpyrrolase reaction which is evidently disturbed in neurooncological patients.

[Diagnosis of hypertensive syndromes of unclear origin (according to the results of radionuclide cisternography)]. / Diagnostika gipertenzionnogo sindroma neiasnogo geneza (po dannym radionuklidnoi tsisternografii).

Analysis of the findings of radionuclide cisternography in 34 patients with a hypertension syndrome of unclear genesis allowed 3 variants of an aggregate of radiological signs to be distinguished. The 1st and 2nd variants indicate diminution of the drainage function of the cerebral submeningeal space, which does not exclude the presence of a pathological process, one of tumorous genesis among others. The third variant which reveals open internal hydrocephalus (ventricular hydrocephalus) with diminished drainage activity of the submeningeal space of the brain excludes the existence of a three-dimensional pathological process, that of tumorous origin also. In hypertension syndrome of unclear genesis disturbed circulation of cerebrospinal fluid was always attended by its impaired resorption; not only a diminished reaction (function) but an accelerated reaction of drainage of the cerebrospinal fluid from its passages may occur when the maintaining drainage function of the submeningeal space of the spinal cord is manifested.

[Assessment of reinnervation of the muscles of facial expression following plastic repair of the facial nerve with the descending branch of the hypoglossal nerve (according to electromyographic findings)]. / Otsenka reinnervatsii mimicheskikh myshts posle plastiki litsevogo nerva niskhodiashchei vetv'iu pod''iazychnogo nerva (po dannym élektromiografii)

The data of electromyographic studies of the bioelectrical activity of the facial muscles following plastic repair of the facial nerve with the aid of the descending branch of the hypoglossal nerve permit to interpret the succession and quality of the reinnervation of the muscles. Myoelectrogenesis, as shown by the examinations of 13 patients, develops earlier and with greater completeness in the muscles around the mouth than in the orbicular eye muscle and the frontal muscle, which corresponds to the clinical observations. In the process of reinnervation the activity of the zygomaticus muscle favoured the formation of joint and voluntary movements of the orbicular muscle of the eye and of the frontal muscle.