RESUMO
BACKGROUND: Clear cell carcinoma of the ovary (CCC) is a rare variety of ovarian cancer. CASE: A case of CCC in a 49-year-old woman was diagnosed in asciticfluid on thin-layer preparations. Peritoneal fluid cytology revealed papillary clusters of cells with clear cytoplasm and extracellular hyaline material generally without neoplastic cells. The tumor was excised, and the histologic sections confirmed the cytologic diagnosis. CONCLUSION: CCC has a distinctive cytomorphologic appearance, and the entity may be diagnosed on ascitic fluid cytology.
Assuntos
Adenocarcinoma de Células Claras/diagnóstico , Ascite/etiologia , Ascite/patologia , Neoplasias Ovarianas/diagnóstico , Adenocarcinoma de Células Claras/complicações , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias Ovarianas/complicações , Tomografia Computadorizada por Raios XRESUMO
Se presenta un caso de carcinoma peritoneal primario extraovárico. Este raro e interesante tumor se caracteriza por una carcinomatosis peritoneal y por un patrón histológico similar al del carcinoma papilar seroso de ovario, pero sin comprometer o sólo afectando microscópicamente la superficie de los ovarios. La paciente presentaba hinchazón abdominal, ascitis con citología positiva y el CA-125 elevado en el suero. En el momento de la cirugía se encontró una afectación peritoneal difusa o multifocal, existiendo afectación microscópica de la superficie serosa ovárica. Las células tumorales fueron positivas para citoqueratina (AE1/AE3), antígeno de membrana epitelial, B72.3, Ber- EP4, Leu-M1, p53, antígeno carcinoembrionario, fosfatasa alcalina placentaria, proteína S-100, CA-125 y receptores estrogénicos
One case of extraovarian primary peritoneal carcinoma is reported. This rare interesting tumor is characterized by a peritoneal carcinomatosis with ascites and by a histological pattern similar to ovarian serous papillary carcinoma, but it either spares the ovaries or involves the surface of the ovaries only microscopically. The patient had abdominal swelling, ascites with positive cytology, and elevated serum CA-125. At surgery multifocal or diffuse peritoneal involvement was found. Microscopic ovarian serosal surface involvement was demonstrated. Tumor cells stained positive for cytokeratin (AE1/AE3), epithelial membrane antigen, B72.3, Ber-EP4, Leu-M1, p53, carcinoembryonic antigen, placental alkaline phosphatase, S-100, CA-125, and estrogen receptors
