1.
Chem Asian J
; 19(14): e202400310, 2024 Jul 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38715395
RESUMO
A novel gold (I)-catalyzed synthetic strategy has been achieved for an efficient construction of indenylidene derivatives from substituted 1,6-diynes. This reaction describes the unique reactivity of gold catalysis in facilitating the intramolecular [3,3]-sigmatropic rearrangement, 5-exo dig cyclization followed by 1,5-migration of acryl group, resulting in the formation of substituted indenylidenes. Various substituted indenylidenes were successfully synthesized with up to 92 % yields. In this protocol, two new C-C bonds were sequentially formed atom economically in one pot.