RESUMO
Hamartoma of the breast is an uncommon tumor like condition constituting only 3.9 to 4.8 % of benign breast tumors. We wish to report clinical, cytological, cytological histological findings of breast hamartoma with pregnancy
Assuntos
Doenças Mamárias/complicações , Doenças Mamárias/patologia , Hamartoma/complicações , Hamartoma/patologia , Complicações na Gravidez/patologia , Adulto , Neoplasias da Mama/complicações , Neoplasias da Mama/diagnóstico , Diagnóstico Diferencial , Feminino , Humanos , Gravidez , Complicações Neoplásicas na Gravidez/diagnósticoRESUMO
Enlarged thyroid with retrosternal extension presenting as anterior mediastinal mass is known. Superior vena cava (SVC) syndrome due to direct invasion from a primary thyroid malignancy is a rare phenomenon. We present a unique case of papillary carcinoma of thyroid extending into the posterior mediastinum with superior vena cava syndrome along with internal jugular and azygous vein thrombosis.
Assuntos
Carcinoma Papilar/complicações , Neoplasias do Mediastino/etiologia , Síndrome da Veia Cava Superior/etiologia , Neoplasias da Glândula Tireoide/complicações , Humanos , Masculino , Neoplasias do Mediastino/diagnóstico por imagem , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
A case of a 21 years male patient with type 3 glycogen storage disorder diagnosed at necropsy, who died suddenly with hypovolemic shock following a massive upper gastrointestinal bleeding due to hepatocellular failure is reported. Salient features of GSD type 3 are briefly discussed.
Assuntos
Hemorragia Gastrointestinal/patologia , Doença de Depósito de Glicogênio Tipo III/patologia , Falência Hepática Aguda/patologia , Dor Abdominal/diagnóstico , Dor Abdominal/etiologia , Adulto , Autopsia , Biópsia por Agulha , Terapia Combinada , Progressão da Doença , Evolução Fatal , Hemorragia Gastrointestinal/etiologia , Hemorragia Gastrointestinal/terapia , Doença de Depósito de Glicogênio Tipo III/complicações , Doença de Depósito de Glicogênio Tipo III/terapia , Humanos , Imuno-Histoquímica , Índia , Falência Hepática Aguda/etiologia , Falência Hepática Aguda/terapia , Masculino , Índice de Gravidade de DoençaRESUMO
A 62-year-old man with recurrent inflammatory pseudotumor of the small bowel mesentery presented with perforative peritonitis; such a presentation has not been reported. The mass was excised successfully.
Assuntos
Granuloma de Células Plasmáticas/complicações , Doenças do Íleo/complicações , Doenças do Jejuno/complicações , Peritonite/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , RecidivaRESUMO
Twenty seven ANA and dsDNA positive cases were selected from surgical files from years 1986 to 1997. Clinical, biochemical, morphological and immunofluorescence findings were correlated. Routine Haematoxylin and Eosin, Per iodic-Acid-Schiff and Methaneamine-Silver stains were used for all cases. Direct immunofluorescence was done whenever possible. Morphologically cases were grouped as per WHO criteria. Morphologically cases were quantified into Austin's chronicity and activity indices. Twenty one to thirty years was common age group. M:F:: 1:4.4. Anemia, skin rash and arthralgia were common extra-renal manifestations. There were 1,5,7,10 and three cases as per WHO class I to V respectively. All cases of class IV had active urine sediments and proteinuria. Four cases had high BUN and Serum creatinine levels. All (12) cases of immunofluorescence revealed group specific patterns. Five cases died. Infection was common cause of death. Twenty to thirty years, males, High BUN and Creatinine levels and high activity and chronicity indices were associated with poor prognosis.
Assuntos
Rim/patologia , Adolescente , Adulto , Biópsia , Feminino , Humanos , Nefrite Lúpica/diagnóstico , Nefrite Lúpica/imunologia , Nefrite Lúpica/metabolismo , Nefrite Lúpica/patologia , Masculino , Pessoa de Meia-Idade , PrognósticoRESUMO
OBJECTIVES: Primary primitive neuroectodermal tumor (PNET) of the kidney is an extremely rare entity and the case is presented to highlight the histological diagnostic problems. METHODS AND RESULTS: A 23-year-old female presented with a lump in the left hypochondrium that had appeared 3 months, earlier, which suggested a malignancy on radiological investigation. The nephrectomy specimen revealed a large tumor mass with only a small portion of normal renal parenchyma. Histology showed a small cell malignant tumor and the diagnosis of PNET (primary of kidney) and small cell carcinoma were suspected. The tumor showed NSE and vimentin positivity and cytokeratin negativity, which conformed with the diagnosis of PNET. CONCLUSION: The biological behaviour of PNET is more aggressive, with rapid progression and infiltration into the surrounding tissues and distant metastases. Thus it differs from the small renal cell malignancies and hence recognition of this tumor as a distinct entity is essential.
Assuntos
Neoplasias Renais/patologia , Tumores Neuroectodérmicos Primitivos/patologia , Adulto , Feminino , HumanosRESUMO
OBJECTIVE: The clinical presentation of adenocarcinoma is not different from the usual transitional cell carcinoma, hence the histological diagnosis plays an important role in the interpretation of cystoscopic biopsies. Six cases of primary adenocarcinoma of the urinary bladder are described from the pathologist's point of view. The diagnostic problems encountered in these cases are highlighted. METHODS: 6 cases of primary adenocarcinoma of the urinary bladder were encountered from 1983 to 1997. Relevant clinical data were analyzed. Multiple sections from the tumor and adjoining areas of the bladder were studied. Five patients were aged 50 to 75 years and the youngest patient was 22 years old. RESULTS: Hematuria and retention of urine were common presenting symptoms. Histologically, the diagnostic problems faced were mucinous metaplasia vs mucinous carcinoma, clear cell adenocarcinoma of the urinary bladder vs clear cell carcinoma of the pelvic kidney. We had one case of urachal and 5 cases of non-urachal carcinoma. CONCLUSIONS: Primary adenocarcinoma of the urinary bladder is an unusual tumor accounting for 0.5 to 2% of all bladder malignancies. They are commonly seen in endemic areas like schistosomiasis. By origin they are grouped into urachal and non-urachal carcinoma and histologically grouped as enteric, mucinous, clear cell and adenocarcinoma not otherwise specified. Direct consultation with the urologist, clinical findings, investigations and careful screening of histological material will help the pathologist to arrive at a correct diagnosis.
Assuntos
Adenocarcinoma/patologia , Neoplasias da Bexiga Urinária/patologia , Adenocarcinoma de Células Claras/patologia , Adenocarcinoma Mucinoso/patologia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Mucosa/patologia , Bexiga Urinária/patologiaRESUMO
The infant autopsies were scrutinised to find the incidence, etiology & significance in terms of fatality of urinary tract anomalies. On analysing 1329 infant autopsies, 24 cases (1.8%) of significant urinary tract anomalies were found. There was marked male predominance. Intrauterine obstruction of urinary tract was the main etiological factor leading to dysplastic changes in the renal tissue. Dysplasia is severe in extent and may be associated with persistent blastemal zones when the obstruction is complete & bilateral in nature.
Assuntos
Rim/anormalidades , Autopsia , Anormalidades Congênitas/mortalidade , Feminino , Humanos , Índia/epidemiologia , Lactente , MasculinoRESUMO
A rare case of paratesticular myxoliposarcoma spreading to the inguinal region forming satellite nodules, hence clinically mimicking a metastatising testicular malignancy is reported. Its prognostic factors are discussed.