[Correlation between elevated maternal serum alpha-fetoprotein, certain pregnancy complications and fetal death]. / Emelkedett anyai szérum alfa-fötoprotein szint összefüggése bizonyos terhességi szövödményekkel és a magzati halálozással.

In a prospective epidemiological study of 23,792 singleton pregnancies the authors investigated the relationship between elevated maternal serum alfa-fetoprotein level and the risk of pathological pregnancy outcome. It has been found that elevated level of maternal alfa-fetoprotein (above 2.5 MoM) is associated with a higher risk of pathological pregnancies and an increased risk of subsequent fetal death. Physicians should be aware of the benefits of the maternal alpha-fetoprotein screening not only in the context of prenatal detection of congenital defects, but also in early identification of increased risk of certain obstetric complications.

[Effect of oral contraceptives on developmental anomalies and on the sex ratio of newborn infants]. / Az orális kontraceptivumok hatása a fejlödési rendellenességek és az újszülöttek nemi arányának alakulására.

Several studies have suggested that maternal use of oral contraceptives before and early pregnancy may be associated with various congenital malformations. It had been found according to the computer-analysis of epidemiologic data of 17,031 single pregnancies--the use of oral contraceptives taken prior to conception or during early pregnancy has not been proved to increase the frequencies of the malformation of the offspring. On the other hand it was found, that oral contraception used before and in the early pregnancy increases the chance that infants delivered subsequently will be female.