RESUMO
BACKGROUND: Overweight and obesity among adults are a growing global public health threat and an essential risk factor for various noncommunicable diseases. Although intermittent fasting is a generally new dietary approach to weight management that has been increasingly practiced worldwide, the effectiveness of 2 days per week dry fasting remains unclear. OBJECTIVE: The Cardiometabolic and Anthropometric Outcomes of Intermittent Fasting study aims to determine the cardiometabolic, anthropometric, dietary intake, and quality of life changes among civil servants with overweight and obesity, following combined intermittent fasting and healthy plate (IFHP) and healthy plate (HP) and explore the participants' experiences. METHODS: We designed a mixed methods quasi-experimental study to evaluate the effectiveness of the IFHP and HP methods among adults with overweight and obesity. A total of 177 participants were recruited for this study, of which 91 (51.4%) were allocated to the IFHP group and 86 (48.6%) to the HP group. The intervention comprised 2 phases: supervised (12 weeks) and unsupervised (12 weeks). Data collection was conducted at baseline, after the supervised phase (week 12), and after the unsupervised phase (week 24). Serum and whole blood samples were collected from each participant for analysis. Data on sociodemographic factors, quality of life, physical activity, and dietary intake were also obtained using questionnaires during data collection. RESULTS: Most of the participants were female (147/177, 83.1%) and Malay (141/177, 79.7%). The expected outcomes of this study are changes in body weight, body composition, quality of life, physical activity, dietary intake, and cardiometabolic parameters such as fasting blood glucose, 2-hour postprandial blood glucose, hemoglobin A1c, fasting insulin, and lipid profile. CONCLUSIONS: The Cardiometabolic and Anthropometric Outcomes of Intermittent Fasting study is a mixed methods study to evaluate the effectiveness of combined IFHP and HP interventions on cardiometabolic and anthropometric parameters and explore participants' experiences throughout the study. TRIAL REGISTRATION: ClinicalTrials.gov NCT05034653; https://clinicaltrials.gov/ct2/show/NCT05034653. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR1-10.2196/33801.
RESUMO
Introduction: the success of controlling pandemics like COVID-19 can be achieved through its vaccination program. Besides masks, social distance, and good hand hygiene, a rapid vaccine program is crucial in controlling this COVID-19 pandemic. Thus, this study aimed to assess the attitudes and perceptions of Nigerians regarding accepting the COVID-19 vaccine. Methods: a cross-sectional study was carried out among 334 respondents aged 18 and above from the Southeastern region of Nigeria. A validated questionnaire was used for the data collection through an online Google form. The data analysis was done using SPSS version 25. The association of socio-demographics with attitudes and perceptions was analysed using chi-square tests and Fisher exact tests. At the 95 percent confidence level, a p-value of 0.05 was deemed statistically significant. Results: sixty point two percent (60.2%) (n = 201) of respondents showed positive attitudes with a mean of (13.96±2.97). Gender was the only demographic factor associated with attitudes (p< 0.001). Respondents with poor perceptions were higher by 53.0% (n = 177) with a mean value of (3.30±1.17). Age, education, gender, and marital status were seen to be associated with perceptions of vaccine acceptance (p<0.05). There was a link between attitudes and perceptions (P> 0.001), as those with positive attitudes also exercised good perceptions. Conclusion: this study revealed that respondents had positive attitudes regarding COVID-19 vaccination acceptance but negative perceptions of it. As a result, community and health promotion professionals, religious leaders, and local celebrities should use their platforms to raise awareness about the benefits of COVID-19 immunization.
