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1.
Ethiop J Health Sci ; 25(1): 79-88, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25733788

RESUMO

BACKGROUND: Several factors including emotional intelligence affect the efficiency of people. It seems that organizational behavior of each person is strongly influenced by emotional intelligence. Therefore, the present study is aimed to examine the relationship between emotional intelligence and organizational citizenship behavior in critical and emergency nurses in teaching hospitals supervised by Kerman Medical University in Southeast of Iran. METHODS: This study employed a descriptive cross sectional design. A census sample consisted of 150 critical and emergency nurses working in teaching hospitals supervised by Kerman Medical University participated in this study. Emotional intelligence and organizational citizenship behavior questionnaire was used to assess nurses' emotional intelligence and organizational citizenship behavior by available sampling method. RESULTS: The results showed that the mean age of the participants was 35 years. Most participants (94%) were females and belonged to the age group of 26-30 years. Overall mean score of organizational citizenship behavior scale was 88.21 (±10.4). In the organizational citizenship behavior categories, altruism mean score was higher than the other mean scores. Overall mean score of emotional intelligence was (121.08 ± 17.56). In the subgroups of emotional intelligence, mean score of the relationship management, was higher than the average of other factors. Pearson's correlation coefficient showed no significant relationship between emotional intelligence and organizational citizenship behavior (p ≥ 0.05). CONCLUSIONS: The study suggests that health care managers should organize systematic and dynamic policies and procedures in dealing with emotional intelligence and organizational citizenship behavior to assist critical and emergency nurses.


Assuntos
Altruísmo , Inteligência Emocional , Recursos Humanos de Enfermagem Hospitalar/psicologia , Adulto , Atitude do Pessoal de Saúde , Comportamento Cooperativo , Cuidados Críticos , Estudos Transversais , Serviços Médicos de Emergência , Emprego , Feminino , Comportamento de Ajuda , Humanos , Relações Interpessoais , Irã (Geográfico) , Masculino , Pessoa de Meia-Idade , Comportamento Social , Inquéritos e Questionários , Trabalho , Adulto Jovem
2.
Drug Deliv ; 21(3): 155-63, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24107075

RESUMO

The objective of this study was to develop pH-responsive silica nanoparticles by imidazole-based ionic liquid for controlled release of methotrexate. In this article, we synthesized pH-responsive cationic silica nanoparticles by graft copolymerization of vinyl functionalized silica nanoparticles and methacrylic acid (MAA) monomer. Imidazole-based ionic liquid (Im-IL) was verified by (1)HNMR and Fourier-transform infrared (FTIR) spectroscopy. The synthesized functionalized silica particles were characterized and confirmed by various technologies including the scanning electron microscopy (SEM), the infrared spectroscopy (IR) and the thermogravimetric analysis (TGA). SEM results reveal the uniformity in size/shape of silica particles. This nanosystem is modified for targeted delivery of an anticancer agent methotrexate. The nanocomposite-MTX complex was formed at physiological pH (7.4) due to the electrostatic interactions between anionic carboxylic group of MTX molecules and cationic rings in carrier, while, the release of which can be achieved through the cleavage of the nanocomposite-MTX complex by protonation of carboxyl groups in the MTX segment that are sensitive to variations in external pH at weak acidic conditions. FT-IR spectroscopy showed the presence of light interactions between the silicate silanols and the drug. MCF7 cells were incubated with the MTX-free nanocomposite and MTX-loaded nanocomposite at various concentrations for 24, 48 and 72 h, and the data showed that the nanocomposites themselves did not affect the growth of MCF7 cells. Antitumor activity of the MTX-loaded nanocomposites against the cells was kept over the whole experiment process. The results showed that the MTX could be released from the fibers without losing cytotoxicity.


Assuntos
Antimetabólitos Antineoplásicos/química , Materiais Biocompatíveis , Portadores de Fármacos , Metotrexato/química , Nanocompostos , Ácidos Polimetacrílicos/síntese química , Dióxido de Silício/síntese química , Antimetabólitos Antineoplásicos/farmacologia , Proliferação de Células/efeitos dos fármacos , Sobrevivência Celular/efeitos dos fármacos , Química Farmacêutica , Preparações de Ação Retardada , Relação Dose-Resposta a Droga , Humanos , Concentração de Íons de Hidrogênio , Imidazóis/química , Células MCF-7 , Metotrexato/farmacologia , Microscopia Eletrônica de Varredura , Nanotecnologia , Ácidos Polimetacrílicos/toxicidade , Espectroscopia de Prótons por Ressonância Magnética , Dióxido de Silício/toxicidade , Solubilidade , Espectroscopia de Infravermelho com Transformada de Fourier , Tecnologia Farmacêutica/métodos , Termogravimetria , Fatores de Tempo
3.
J Biomed Phys Eng ; 4(4): 141-50, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25599060

RESUMO

BACKGROUND: Recent studies in eye plaque brachytherapy have shown a considerable difference between the dosimetric results using water phantom and a model of human eye containing realistic materials. In spite of this fact, there is a lack of simulation studies based on such a model in proton therapy literatures. In the presented work, the effect of utilizing an eye model with ocular media on proton therapy is investigated using the MCNPX Monte Carlo Code. METHODS: Two different eye models are proposed to study the effect of defining realistic materials on dose deposition due to utilizing pencil beam scanning (PBS) method for proton therapy of ocular melanoma. The first model is filled with water, and the second one contains the realistic materials of tumor and vitreous. Spread out Bragg peaks (SOBP) are created to cover a typical tumor volume. Moreover, isodose curves are figured in order to evaluate planar variations of absorbed dose in two models. RESULTS: The results show that the maximum delivered dose in ocular media is approximately 12-32% more than in water phantom. Also it is found that using the optimized weighted beams in water phantom leads to disturbance of uniformity of SOBP in ocular media. CONCLUSION: Similar to the results reported in eye brachytherapy published papers, considering the ocular media in simulation studies leads to a more realistic assessment of sufficiency of the designed proton beam in tissue. This effect is of special importance in creating SOBP, as well as in delivered dose in the tumor boundaries in proton pencil beam scanning method.

5.
Radiographics ; 16(5): 1207-13, 1996 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-8888400

RESUMO

A software program has been developed that uses a frame-based expert system for differential diagnosis in neuroradiology. A frame-based expert system is used to store the magnetic resonance (MR) and computed tomographic (CT) imaging characteristics of over 100 known brain disorders in object-like entities. The frames are organized in a hierarchic structure in which lower order frames inherit attributes from higher order frames, with the highest frame containing information that applies to all the other frames. Program execution follows a consultation paradigm with a dynamic database. A decision tree menu provides a user-friendly interface with which to navigate through the network, based on features of the lesion as depicted on MR and CT images. The system can provide a differential diagnosis based on the MR imaging findings alone with information criteria including the signal intensity of the lesion on T1- and T2-weighted images, the location of the lesion, and the presence or absence of mass effect. The differential diagnosis may be further refined by adding CT-related information, including CT attenuation and the presence or absence of calcification and contrast enhancement.


Assuntos
Neoplasias Encefálicas/diagnóstico , Diagnóstico por Computador , Sistemas Inteligentes , Encéfalo/diagnóstico por imagem , Encéfalo/patologia , Neoplasias Encefálicas/diagnóstico por imagem , Diagnóstico Diferencial , Humanos , Imageamento por Ressonância Magnética , Tomografia Computadorizada por Raios X
6.
J Air Waste Manag Assoc ; 45(3): 191-5, 1995 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15658159

RESUMO

Many complex models are available to study the dispersion of contaminants or ventilation effectiveness in indoor spaces. Because of the computationally complex numerical schemes employed, most of these models require mainframe computers or workstations. However, simple design tools or guidelines are needed, in addition to complicated models. A dispersion model based on the basic governing equations was developed and uses an analytical solution. Because the concentration is expressed by an analytical solution, the grid size and time steps are user definable. A computer program was used to obtain numerical results and to obtain release history from a thermodynamic source model. The model can be used to estimate three-dimensional spatial and temporal variations in concentrations resulting from transient gas releases in an enclosure. The model was used to study a gas release scenario from a pressurized cylinder into a large ventilated building, in this case, a transit parking and fueling facility.


Assuntos
Poluição do Ar em Ambientes Fechados/análise , Combustíveis Fósseis , Modelos Teóricos , Ventilação , Movimentos do Ar , Automóveis , Estados Unidos
7.
Radiology ; 160(3): 773-80, 1986 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-3737917

RESUMO

Twenty-one patients with intraocular disease were studied by magnetic resonance (MR) imaging and computed tomography (CT). In 13 cases, malignant uveal melanoma was considered the likely diagnosis. Both imaging methods were accurate in determining the location and size of uveal melanomas. MR imaging was superior for the assessment of possible associated retinal detachment, for assessment of vitreous change, and for differentiating uveal melanoma from choroidal hemangioma and choroidal detachment. A case of retinal gliosis could not be differentiated from uveal melanoma by either technique. Uveal melanomas appeared as hyperintense lesions on T1-weighted images and as hypointense lesions on T2-weighted images. High signal intensity of the vitreous was observed in patients with vitritis and in those who were thought to have protein leaking into the vitreous as a result of impairment of the retinal-blood barrier.


Assuntos
Espectroscopia de Ressonância Magnética , Melanoma/diagnóstico , Neoplasias Uveais/diagnóstico , Adulto , Idoso , Corioide/irrigação sanguínea , Meios de Contraste , Diagnóstico Diferencial , Feminino , Gliose/diagnóstico , Hemangioma/diagnóstico , Hemorragia/diagnóstico , Humanos , Masculino , Melanoma/cirurgia , Pessoa de Meia-Idade , Descolamento Retiniano/diagnóstico , Doenças Retinianas/diagnóstico , Tomografia Computadorizada por Raios X , Neoplasias Uveais/cirurgia , Corpo Vítreo/irrigação sanguínea , Corpo Vítreo/lesões
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