1.
Biochem Med Metab Biol
; 42(3): 209-15, 1989 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-2597436
RESUMO
The in vitro self-assembly of Type I rat tail tendon collagen in the presence of monosaccharides was studied turbidimetrically. D(+)glucose and D(+)mannose delayed fibril formation significantly while D(-)fructose showed no variation. The effect of glucose was concentration dependent. Binding of glucose during fibrillogenesis was shown by the incorporation of [14C]glucose and also by SDS-polyacrylamide slab gel electrophoresis of the product. The results indicate that in vitro nonenzymatic glycosylation can take place in the short duration required for fibril formation.
Assuntos
Colágeno/metabolismo , Monossacarídeos/farmacologia , Animais , Colágeno/ultraestrutura , Eletroforese em Gel de Poliacrilamida , Meia-Vida , Cinética , Nefelometria e Turbidimetria , Ratos
2.
Indian J Med Res
; 86: 641-5, 1987 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3451909
3.
Indian J Exp Biol
; 19(8): 715-21, 1981 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-7309156