[The tracheo-team in the management of intracranic pressure during a dilatative tracheostomy in severe head trauma: the impact of a checklist]. / Il tracheo-team nella gestione della pressione endocranicadurante tracheostomia dilatativa nel trauma cranico grave:l'impatto di una checklist.

. The tracheo-team in the management of intracranic pressure during a dilatative tracheostomy in severe head trauma: the impact of a checklist. INTRODUCTION: Percutaneous dilatative tracheostomy (PDT) is a common technique in neurosurgical intensive care. However, it may cause imbalances of brain parameters causing secondary damages. AIM: To assess the intra cranic pressure (ICP) values and the safety of PDT performed by a tracheo-team of doctors and nurses, according to a procedure described in a checklist, in patients with severe head trauma. METHODS: All patients with severe head trauma, admitted from 2005 to 2015, exposed to PDT and with monitoring, before and after the PDT, of brain parameters (ICP and cerebral perfusion pressure) and mechanical ventilation, were included. The PDT was performed according to a checklist developed by the ward staff. RESULTS: 1571 patients with severe head trauma were admitted: 721 underwent a PDT, the ICP was monitored in 422. A temporary increase of ICP (>30mmhg) was overall observed in 11.5% of cases among those with baseline ICP >20, >20 and <10mmhg, respectively in 25, 8 and 4% of cases. Major complications were not observed; minor complications were <4%. CONCLUSIONS: Overall and intracranial hypertension complications PDT related are lower than reported in the literature. A checklist for PDT with tracheo-team of nurses and doctors with experience in neuro intensive care allows a safe and reliable management of the procedure in severe head trauma patients.

How health service delivery guides the allocation of major trauma patients in the intensive care units of the inclusive (hub and spoke) trauma system of the Emilia Romagna Region (Italy). A cross-sectional study.

OBJECTIVE: To evaluate cross-sectional patient distribution and standardised 30-day mortality in the intensive care units (ICU) of an inclusive hub and spoke trauma system. SETTING: ICUs of the Integrated System for Trauma Patient Care (SIAT) of Emilia-Romagna, an Italian region with a population of approximately 4.5 million. PARTICIPANTS: 5300 patients with an Injury Severity Score (ISS) >15 were admitted to the regional ICUs and recorded in the Regional Severe Trauma Registry between 2007 and 2012. Patients were classified by the Abbreviated Injury Score as follows: (1) traumatic brain injury (2) multiple injuriesand (3) extracranial lesions. The SIATs were divided into those with at least one neurosurgical level II trauma centre (TC) and those with a neurosurgical unit in the level I TC only. RESULTS: A higher proportion of patients (out of all SIAT patients) were admitted to the level I TC at the head of the SIAT with no additional neurosurgical facilities (1083/1472, 73.6%) compared with the level I TCs heading SIATs with neurosurgical level II TCs (1905/3815; 49.9%). A similar percentage of patients were admitted to level I TCs (1905/3815; 49.9%) and neurosurgical level II TCs (1702/3815, 44.6%) in the SIATs with neurosurgical level II TCs. Observed versus expected mortality (OE) was not statistically different among the three types of centre with a neurosurgical unit; however, the best mean OE values were observed in the level I TC in the SIAT with no neurosurgical unit. CONCLUSION: The Hub and Spoke concept was fully applied in the SIAT in which neurosurgical facilities were available in the level I TC only. The performance of this system suggests that competition among level I and level II TCs in the same Trauma System reduces performance in both. The density of neurosurgical centres must be considered by public health system governors before implementing trauma systems.

Aggressive versus conservative antibiotic use to prevent and treat ventilator-associated pneumonia in patients with severe traumatic brain injury: comparison of two case series.

BACKGROUND: In patients with traumatic brain injury (TBI), ventilator-associated pneumonia (VAP) is considered a dangerous complication, prompting early aggressive antibiotic treatment and prophylaxis. While this approach increases the selection of multidrug-resistant bacteria (MDR), its clinical benefit has not been demonstrated. METHODS: One-year incidence of VAP in severe TBI patients (ICU stay >48 hours, with either Glasgow Coma Scale ≤8 or receiving intracranial pressure monitoring, or having undergone emergency surgery) and the prevalence of MDR among those who eventually developed it, were compared in two Italian intensive care units (ICUs) adopting different antibiotic approaches. Antibiotic use was guideline-driven and aggressive in the Pisa-based unit (165 eligible patients), and very conservative and coupled with non-pharmacological prevention measures in Cesena (262 patients). Data were also compared with those of 208 Italian ICUs participating in the same infection surveillance program. RESULTS: Patient case mix and general care were similar in the two units. Overall antibiotic pressure was higher in Pisa (58.9% vs. 26.1% of beds occupied by patients receiving antibiotics, P<0.0001), as was antibiotic prophylaxis in eligible patients (87.3% vs. 7.6%, P<0.0001; Italian ICUs, 69.2%) and empirical therapy in those who developed VAP (60.8% vs. 25.2%, P<0.0001; Italian ICUs, 51.6%). The incidence rate of VAP did not significantly differ (39.8 per 1000 days of mechanical ventilation in Pisa, 49.3 in Cesena, P=0.16), although it occurred earlier in Cesena (23.0% early VAP in Pisa vs. 61.2% in Cesena, P<0.0001). Mortality was higher in Pisa but Cesena transferred more patients to other hospitals, precluding comparison of the two rates. The prevalence of MDR was higher in Pisa (38.2% vs. 9.9%, P<0.0001; Italian ICUs, 30.2%). CONCLUSIONS: Although not conclusive, these results call into question the prevalent aggressive use of antibiotics in TBI patients and urge the scientific community to produce better evidence for clinical recommendations.

Global cerebral blood flow and CPP after severe head injury: a xenon-CT study.

OBJECTIVE: To evaluate the association between global cerebral blood flow and different cerebral perfusion pressure ranges in severe head injury. DESIGN: A retrospective study SETTING: Neurosurgical and trauma patients in an intensive care unit in a regional hospital. PATIENTS AND PARTICIPANTS: Out of a series of 237 consecutive patients with severe head injuries (GCS