RESUMO
CASE REPORT: A 62-year-old woman presented with a large rapidly growing violaceous mass initially diagnosed as a chalazion. Histopathologic examination disclosed Merkel cell carcinoma (MCC). Radiotherapy was not tolerated. Despite chemotherapy, she succumbed to widespread metastases 13 months later. COMMENTS: MCC must be included in the differential diagnosis of solitary eyelid nodules, requiring early and aggressive treatment.
Assuntos
Carcinoma de Célula de Merkel/diagnóstico , Calázio/diagnóstico , Neoplasias Palpebrais/diagnóstico , Neoplasias Cutâneas/diagnóstico , Biomarcadores Tumorais/análise , Carcinoma de Célula de Merkel/química , Carcinoma de Célula de Merkel/cirurgia , Diagnóstico Diferencial , Neoplasias Palpebrais/química , Neoplasias Palpebrais/cirurgia , Evolução Fatal , Feminino , Humanos , Pessoa de Meia-Idade , Metástase Neoplásica , Neoplasias Cutâneas/química , Neoplasias Cutâneas/cirurgiaRESUMO
CASE REPORT: A 45-year-old man presented with an orbital tumour that on MRI was most consistent with a hemangioma. Histopathologic examination disclosed an orbital schwannoma, with cystic and mucinous degeneration complicating radiologic interpretation. COMMENTS: An array of ancillary studies including orbital ultrasonography may be useful in substantiating the diagnosis preoperatively.
Assuntos
Imageamento por Ressonância Magnética , Neurilemoma/patologia , Neoplasias Orbitárias/patologia , Biomarcadores Tumorais/análise , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Proteínas de Neoplasias/análise , Neurilemoma/química , Neoplasias Orbitárias/química , Tomografia Computadorizada por Raios X , UltrassonografiaRESUMO
A 40-year-old woman with an orbital lesion presented with a history of slowly progressive proptosis. A thorough systemic workup did not reveal any stigmata of multiple myeloma, and she was treated with a course of orbital radiotherapy. Histopathologic studies of the biopsy specimen revealed a proliferation of neoplastic plasma cells, which produced monoclonal lambda light chains surrounding concretions of congophilic, amorphous material. The lesion was diagnosed as a solitary osseous plasmacytoma of the orbit containing amyloid.
