[Familial myopathy with exclusively cardiac clinical expression]. / Myopathie familiale d'expression clinique exclusivement cardiaque.

A case is presented of a familial form of apparently primary cardio-myopathy with findings on investigation and histology which were in favour of a generalised subclinical muscular disorder: a raised serum creatinine phosphokinase, persistent carnosinuria on a vegetarian diet, and under the light microscope several features indicative of a myogenic dystrophic condition on deltoid biopsy. From their clinical features, these original cases may be classified somewhere between primary familial heart disease and the cardiac complications of myopathies. The value of the creatinine phosphokinase isoenzymes and of muscle biopsy in situations such as these is discussed.

[Unilateral auricular paralysis and dissociated ectopic auricular rhythm. Apropos of 4 cases]. / Paralysies auriculaires unilatérales et rythmes auriculaires actopiques dissociés. A propos de 4 cas

The authors report four cases of right atrial palsy associated with tachycardia and/or slow atrial rhythm from the left auricle in elderly subjects with a past history of cardiac failure with atrial fibrillation for about ten years; they were digitalised and had cardiac failure, and in addition there was one perisinus block and one paroxysmal or persistant complete block situated above the bundle of His and probably above the AV node itself, secondary to the condition of atrial palsy. This probably represents an intermediate stage between chronic atrial fibrillation and atrial palsy in an elderly subject. These cases require careful intracavitary investigation, and often treatment by pacemaker and digitalis.

[Treatment by urokinase of myocardial infarction and threatened infarction. Randomised study of 120 cases]. / Le traitement par l'urokinase des infarctus du myocarde et syndromes de menace. Etude randomisée de 120 cas]

Two randomized series of 60 cases of myocardial infarction or menace syndrome have been treated at the acute stage, one by Heparin alone, the other by the combination Urokinase-Heparin. The average dosage was 300 mg Heparin in the first series, of 2,700,000 CTA units of Urokinase combined with 240 mg of Heparin in the second series. After the first 24 hours, equal heparinization was performed in both series up to the third week. Significantly different results were obtained in the two series. They favour Urokinase and concern: -- the disappearance time of pain, -- the course of the arrhythmias and of cardiac failure, -- the regression or limitation of the necrosis q waves and the lesion areas on the electrocardiogram. Finally the 30th-day overall mortality was 13% in the Heparin series and 3% in the myocardial infarction on the way of constitution, or which have done so for less than 24 hours.