Assuntos
Neoplasias dos Ductos Biliares/diagnóstico , Ducto Colédoco , Cistadenoma/diagnóstico , Equinococose Hepática/diagnóstico , Neoplasias dos Ductos Biliares/cirurgia , Cistadenoma/cirurgia , Diagnóstico Diferencial , Feminino , Humanos , Laparotomia , Tomografia Computadorizada por Raios X , Adulto JovemRESUMO
Primary mesenteric liposarcoma is a rare malignant tumor of mesenchymal origin. These tumors are often found to be of substantial size upon first clinical presentation. We report a case of primary mesenteric liposarcoma in a 55 year old man who underwent laparotomy for the clinical/radiological impression of a mesenteric cyst. FNAC was inconclusive due to suboptimal cellularity. On laparotomy there were 2 masses (diameter- 19 and 14 cms) weighing approximately 8.5 kilograms together. Histopathology showed features of atypical lipomatous tumor / well differentiated liposarcoma (ALT/WDLS) with mixed histological pattern (e.g. lipoma like, sclerosing and myxoid areas) varying from area to area. Prognosis of ALT/WD liposarcoma depends upon its anatomic location and most aggressive histological subtype. This case is being presented because of its huge dimensions, rarity of the site and mixed histological pattern.
Assuntos
Lipossarcoma/diagnóstico , Lipossarcoma/patologia , Mesentério/patologia , Abdome/diagnóstico por imagem , Humanos , Laparotomia , Lipossarcoma/cirurgia , Masculino , Pessoa de Meia-Idade , UltrassonografiaRESUMO
A study was carried out on the effect of gentamicin on the central auditory pathway in rats. Rats were administered graded doses of gentamicin (60 mg, 100 mg and 160 mg/kg b.wt., i.m.) daily for 21 days. Levels of total lipids, phospholipids and cholesterol showed dose related increment in the central auditory pathway. On the other hand, the rate of lipid peroxidation was inhibited in all regions of the central auditory pathway of the rat.