[Clinical manifestations, diagnosis and conservative treatment of slowly healing stomach ulcers]. / Osobennosti klinicheskikh proiavlenii, diagnostiki i konservativnogo lecheniia trudnorubtsuiushchikhsia iazv zheludka.

The paper presents the analysis of examination and treatment data on 80 patients with long-healing gastric ulcer (12 weeks or longer), of contributing factors (sex, age, ulcer site and size, smoking, alcohol abuse, associated diseases), of changes in the antral and fundal gastric mucosa as well as in immune system, of conservative treatment results.

[Esophageal lesions in Cushing's syndrome and corticosteroma]. / Porazheniia pishchevoda pri bolezni Itsenko-Kushinga i kortikosterome.

The state of the esophagus was studied in 60 patients with endogenous hypercorticism (2 with corticosteroma, 58 with Icenko-Cushing disease). The purpose was to reveal the nature and frequency of esophageal lesions and peculiarities of their clinical symptoms. X-ray and endoscopic methods were used. Functional and organic esophageal changes were shown to be rather common in patients with excess of body glucocorticoids: hypomotor dyskinesia was noted in 27% of the patients, cardial insufficiency in 13%, cardial hernia of the esophageal orifice of the diaphragm in 28%, reflux-esophagitis in 43%. Cardial hernia and esophagitis in such patients are often characterized by weak clinical symptoms masked by other signs of severe endocrine pathology. They can be also symptomless making their early diagnosis difficult. However these esophageal diseases are fraught with danger and life threatening complications: ulcerations, perforations, esophageal hemorrhages aggravating a course of the main disease. These patients need appropriate therapy to avoid complications.