1.
Chem Commun (Camb)
; 51(51): 10276-9, 2015 Jun 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25921612
RESUMO
A novel, I2 catalyzed regio- and stereodivergent vicinal azidohydroxylation of alkenes leading to 1,2-azidoalcohols in high yields (up to 92%) and excellent dr (up to 98%) has been developed. This unprecedented transformation employs NaN3 and DMF as N- and O-nucleophiles respectively. The role of DMF as the O-source in the reaction has been unequivocally proven by (18)O labelling studies.