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2.
J Biomed Mater Res B Appl Biomater ; 90(2): 952-61, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19165769

RESUMO

A leaflet escape occurred in a low profile bileaflet mechanical prosthesis manufactured by TRI-Technologies that had been implanted for 3 years in the mitral position of a 32 year old patient. The escaped leaflet had embolized and was subsequently located by an abdominal computerized axial tomography scan and ultrasound in the terminal portion of the aortic bifurcation. The embolized leaflet was removed 3 months after valve replacement surgery. In an attempt to determine the cause of the escape the retrieved embolized leaflet was investigated. Techniques employed included visual examination aided by stereo-microscopy, x-ray imaging and scanning electron microscopy. One of the ears had fractured and was missing from the leaflet. Chipping was observed at the leaflet ear position on both the inflow and outflow surfaces. Visual and SEM observations found fractographic river-lines that indicated an apparent origin at the inflow surface of the ear nearest to the straight 'B-datum' line or coaptation edge. The origin seemed to be in the radius between the leaflet ear and the leaflet body. SEM observation of the remaining intact ear showed wear marks on both the inflow and outflow sides of the leaflet ear that corresponded to the suspected origin of fracture. It is believed that the use of boron alloyed pyrolytic carbon material and the leaflet's homogeneous monolithic structural design were factors that contributed to this adverse event.


Assuntos
Implante de Prótese de Valva Cardíaca/efeitos adversos , Próteses Valvulares Cardíacas/efeitos adversos , Falha de Prótese , Adulto , Carbono/química , Remoção de Dispositivo , Humanos , Microscopia Eletrônica de Varredura/métodos , Valva Mitral/patologia , Próteses e Implantes/efeitos adversos , Desenho de Prótese/efeitos adversos , Raios X
3.
Eur J Echocardiogr ; 8(4): 302-6, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16781196

RESUMO

Marfan's syndrome is a hereditary connective tissue disease, in which cardiovascular abnormalities (especially aortic root dilatation) are the most important cause of morbidity and mortality. In this report, we describe two 24-year-old twins, with a history of surgery for lens subluxation and severe cardiovascular manifestations secondary to Marfan's syndrome. One of the twins suffered a type A aortic dissection, which required replacement of the ascending aorta, and the other twin had an aneurysmal dilatation of the ascending aorta (46mm) and was prescribed medical treatment with atenolol and periodic controls to detect the presence of a critical diameter (50mm) that would indicate the need for prophylactic surgery.


Assuntos
Aorta/diagnóstico por imagem , Aneurisma Aórtico/diagnóstico por imagem , Dissecção Aórtica/diagnóstico por imagem , Síndrome de Marfan/diagnóstico por imagem , Gêmeos Monozigóticos , Adulto , Dissecção Aórtica/etiologia , Aorta/patologia , Aneurisma Aórtico/etiologia , Atenolol/uso terapêutico , Humanos , Masculino , Síndrome de Marfan/complicações , Ultrassonografia
4.
Eur J Echocardiogr ; 8(1): 63-6, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-16434233

RESUMO

Acute prosthetic valve dysfunction due to leaflet escape is a mode of structural valve failure of mechanical prostheses which is associated with a high mortality. In this report, we describe the case of a 32-year-old patient, who underwent mitral valve replacement with a Tri-technologies bileaflet valve three years ago, and was admitted to the hospital on August 2005, in cardiogenic shock. He discontinued oral anticoagulation therapy four months ago. Transthoracic and transesophageal echocardiograms showed acute-onset massive mitral regurgitation with normal left ventricular function. The patient underwent emergency surgery, during which one leaflet was found to be absent and the other leaflet was fixed due to prosthetic thrombus.


Assuntos
Próteses Valvulares Cardíacas/efeitos adversos , Insuficiência da Valva Mitral/etiologia , Valva Mitral/patologia , Falha de Prótese , Doença Aguda , Humanos , Valva Mitral/diagnóstico por imagem , Insuficiência da Valva Mitral/diagnóstico por imagem , Insuficiência da Valva Mitral/cirurgia , Choque Cardiogênico/etiologia , Ultrassonografia
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