RESUMO
The clinical significance of contaminated ocular cosmetics is illustrated by the case of a 47-year-old woman in whom a Pseudomonas corneal ulcer developed immediately after she sustained minor corneal trauma with a mascara applicator. Pseudomonas aeruginosa was cultured from the corneal ulcer and the mascara. In addition to the causative role in acute corneal ulcers, contaminated eye cosmetics contribute to chronic external eye infections. Retail eye cosmetics are typically free of contamination when purchased. The inoculation of the cosmetic occurs during normal use.
Assuntos
Lesões da Córnea , Úlcera da Córnea/etiologia , Cosméticos/efeitos adversos , Infecções por Pseudomonas/etiologia , Antibacterianos/uso terapêutico , Opacidade da Córnea/etiologia , Úlcera da Córnea/tratamento farmacológico , Úlcera da Córnea/microbiologia , Feminino , Humanos , Pessoa de Meia-Idade , Pseudomonas aeruginosa/isolamento & purificaçãoRESUMO
The effectiveness of fluorometholone was compared to dexamethasone phosphate and prednisolone acetate in preventing the immune corneal graft reaction in rabbits. Clear corneal grafts were obtained. Rejection was induced after skin from the corneal donor animal was grafted subcutaneously in the host animal and the animals were randomized into four treatment groups. Rejection occurred in eight of nine rabbits in the control group; one of eight in the dexamethasone phosphate group; one of eight in the fluorometholone group; and one of ten in the prednisolone acetate group. Histologic examination confirmed the above findings. In this animal study fluorometholone prevented immune graft rejection in a percentage similar to that of prednisolone acetate and dexamethasone phosphate.
