RESUMO
Proplast II disc implants (Vitek Inc, Houston) were used in nine patients (14 joints) who underwent discectomy of the temporomandibular joint (TMJ). These patients subsequently underwent removal of the implants from 10 to 28 months postplacement due to pain and occlusal changes or radiographic changes in the joints. Light and electron microscopic evaluations were performed on the retrieved implants and surrounding tissue. Evidence of gross deterioration manifested by fracture of the implant was present in 10 of the 14 implants, and microscopic evidence of deterioration was present in all implants. Foreign-body giant cell reaction in surrounding tissues and microfragmentation of the implant were evident in all joints.
Assuntos
Óxido de Alumínio , Alumínio , Cartilagem Articular/ultraestrutura , Reação a Corpo Estranho/patologia , Luxações Articulares/cirurgia , Politetrafluoretileno , Proplast/análogos & derivados , Próteses e Implantes , Transtornos da Articulação Temporomandibular/patologia , Articulação Temporomandibular/ultraestrutura , Adulto , Idoso , Materiais Biocompatíveis , Cartilagem Articular/cirurgia , Estudos de Avaliação como Assunto , Feminino , Reação a Corpo Estranho/etiologia , Humanos , Luxações Articulares/patologia , Masculino , Microscopia Eletrônica , Pessoa de Meia-Idade , Articulação Temporomandibular/cirurgia , Transtornos da Articulação Temporomandibular/cirurgiaRESUMO
By use of a modified heat-suction, skin blister technique, we found that oral hydroxyzine, 25 mg four times a day, inhibits antigen-induced ultrastructural changes of mast cells and in vivo histamine release in the skin of ragweed-sensitive individuals. To our knowledge this is the first demonstration that an orally active antihistamine can inhibit in vivo cutaneous anaphylactic reactions.
