Assuntos
Eosinofilia/diagnóstico , Eosinofilia/tratamento farmacológico , Eosinofilia/patologia , Fáscia/patologia , Fasciite/diagnóstico , Fasciite/tratamento farmacológico , Fasciite/patologia , Adulto , Artrite/etiologia , Biópsia , Doença Crônica/tratamento farmacológico , Colchicina/análogos & derivados , Colchicina/uso terapêutico , Edema/etiologia , Eosinofilia/etiologia , Fáscia/diagnóstico por imagem , Ácido Fólico/uso terapêutico , Humanos , Masculino , Mialgia/etiologia , Prednisona/uso terapêutico , Recidiva , Sinovite/etiologia , Ácido Ursodesoxicólico/uso terapêutico , Vitamina E/uso terapêutico , Índias OcidentaisRESUMO
Antidepressant withdrawal symptoms, following abrupt or gradual discontinuation of antidepressants, include general somatic distress (flu-like syndromes, gastro-intestinal disturbances, myalgias, headache, chills, weakness and rhinorrhea), anxiety, agitation, sleep disturbances, movement disorders, cardiac arrhythmias, delirium and manic reactions. Two cases of delirium, an hypomanic reaction and two general distress and movement disorders are reported. Cases 1 and 2 required admission to a general hospital. The etiology of the delirium was difficult to assess as long as the clinicians did not know that patients were taking antidepressants. Case 3 corresponds to the paradoxical activation following antidepressant interruption. Cases 4 and 5 constitutes light withdrawal syndromes. Most of cases are probably unrecognized. These cases reflect the importance in daily practice of the phenomena. It can be concluded from our study that: antidepressants must not be abruptly discontinued when a somatic disease appears. When a patient treated with a psychotropic drug develops delirium, the withdrawal of antidepressant must be suspected and the prescribing physician contacted to know what kind of psychoactive medication was prescribed.
Assuntos
Antidepressivos Tricíclicos/efeitos adversos , Transtorno Depressivo/tratamento farmacológico , Síndrome de Abstinência a Substâncias , Transtorno Bipolar , Confusão/induzido quimicamente , Transtorno Depressivo/complicações , Discinesia Induzida por Medicamentos/etiologia , Feminino , Humanos , Masculino , Transtornos Somatoformes/induzido quimicamente , Transtornos Relacionados ao Uso de Substâncias/diagnósticoRESUMO
A fluorimetric and a colorimetric method for the determination of hydrogen peroxide (H2O2) production by isolated cells were compared. Despite a higher sensitivity of the fluorimetric assay, using homovanillic acid (HVA) as reagent, a significantly lower H2O2 production by rat pleural macrophages was measured in comparison to the colorimetric phenol red method. A negative influence of HVA on H2O2 production was detected in the colorimetric assay. These results suggest that the fluorimetric assay with HVA is unsuitable for determining H2O2 formation by isolated cells.
