RESUMO
43 brain cavernous angiomas (CA) were clinically and morphologically studied. The presence of smooth muscles and endotheliocytes in the trabeculae was confirmed. The sources of blood supply and the nature of medullary changes at the CA periphery were clarified. The hypothesis of CA hormonal dependence has been rejected.
Assuntos
Neoplasias Encefálicas/patologia , Hemangioma Cavernoso do Sistema Nervoso Central/patologia , Adolescente , Adulto , Idoso , Neoplasias Encefálicas/ultraestrutura , Criança , Feminino , Hemangioma Cavernoso do Sistema Nervoso Central/ultraestrutura , Humanos , Imuno-Histoquímica , Masculino , Microscopia Eletrônica , Microscopia Eletrônica de Varredura , Pessoa de Meia-IdadeRESUMO
Only a third of the cases who have neurosurgical abnormality has been found to develop irreversible hypothalamus affections caused by tumor growth, hemorrhages, and ischemic infarcts. Microcirculatory abnormalities made up three typical morphological variants, viz. venous congestion, impaired rheological and coagulative properties of blood, and anemia in the vasculature predominantly occur in the other cases. Acute bilateral destruction in the medial segments of the hypothalamus corresponds to its profound functional inhibition. As its morphological substrate, sharp irritation of the hypothalamus (the diencephalic and catabolic syndrome has widespread rheological and coagulative abnormalities in its structures associated with largely reversible dystrophic changes in nerve cells.
Assuntos
Encefalopatias/patologia , Eletroencefalografia , Hipotálamo/patologia , Adulto , Animais , Encefalopatias/fisiopatologia , Encefalopatias/cirurgia , Isquemia Encefálica/patologia , Isquemia Encefálica/fisiopatologia , Isquemia Encefálica/cirurgia , Neoplasias Encefálicas/patologia , Neoplasias Encefálicas/fisiopatologia , Neoplasias Encefálicas/cirurgia , Hemorragia Cerebral/patologia , Hemorragia Cerebral/fisiopatologia , Hemorragia Cerebral/cirurgia , Feminino , Humanos , Hipotálamo/fisiopatologia , Masculino , Pessoa de Meia-Idade , RatosRESUMO
Hypothalamic disorders develop often in neurosurgical patients in the clinic. Complex study of the condition of the hypothalamic structures disclosed a relationship between the pronounced character of the disorders of the vegetative functions, changes of the EEG values according to the degree of alpha-rhythm maintenance, and the morphological changes of the hypothalamus. The results obtained can be used in working out the most adequate pathogenetic therapy.
