RESUMO
The study covered analysis of reproductive function, incidence of chronical diseases and gynecologic malignancies in rubber female workers. Hazardous work conditions of rubber production were reported to afflict reproductive function promoting gynecologic diseases and to change the structure of oncologic morbidity. Female workers exposed to occupational hazards of rubber production show some long-term effects of the exposure such as reliably increased reproductive impairments. Mechanism of such impairments may be connected with endocrine disbalance especially with estrogen deficit. As a result of it the changed ratio breast/uterus and ovary cancers is found among female rubber workers in comparison with the general population.
Assuntos
Indústria Química , Doenças dos Genitais Femininos/induzido quimicamente , Neoplasias dos Genitais Femininos/induzido quimicamente , Doenças Profissionais/induzido quimicamente , Exposição Ocupacional , Reprodução/efeitos dos fármacos , Borracha/efeitos adversos , Adulto , Doença Crônica , Estudos de Coortes , Feminino , Doenças dos Genitais Femininos/epidemiologia , Neoplasias dos Genitais Femininos/epidemiologia , Humanos , Incidência , Morbidade , Doenças Profissionais/epidemiologiaAssuntos
Aborto Induzido/efeitos adversos , Neoplasias da Mama/etiologia , Adulto , Feminino , Humanos , Paridade , Gravidez , Fatores de RiscoRESUMO
The analysis of publications reveals that this professional risk-group of females is marked by an increase of obstetrical pathology, fetal death and inborn malformations. Animal experiments proved teratogenicity, embryotoxicity and mutagenicity of some compounds to which women are exhibited in resin and plastic producing industries. Increased chromosomal abbreviations have been revealed in somatic cells and embryonal tissue fibroblasts. Elaboration of further preventive measures is needed to lower the risk of health affects in female workers and their children.