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1.
Front Endocrinol (Lausanne) ; 14: 1216507, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37711903

RESUMO

Objective: This study aimed to evaluate the association between blood heavy metal (zinc (Zn), copper (Cu), lead (Pb), and cadmium (Cd)) concentrations and spontaneous abortion (SA) and recurrent pregnancy loss (RPL) and explore the possible endocrine dysfunction associated with it. Methods: A literature search was performed in the PubMed, Embase, Cochrane Library, and Web of Science databases up to April 2023. The overall effects were expressed as the standard mean difference (SMD). Subgroup analysis was performed according to the type of abortion (SA or RPL). Stata 16.0 was utilized for data analysis. Results: Based on the integrated findings, abortion women showed significantly lower Zn (SMD = -1.05, 95% CI: -1.74 to -0.36, p = 0.003) and Cu concentrations (SMD = -1.42, 95% CI: -1.97 to -0.87, p <0.001) and higher Pb (SMD = 1.47, 95% CI: 0.89-2.05, p <0.001) and Cd concentrations (SMD = 1.15, 95% CI: 0.45-1.85, p = 0.001) than normal pregnant women. Subgroup analysis showed that Zn and Cu deficiency and Cd and Pb exposure were significantly (p <0.05) associated with RPL, whereas Cu deficiency and Cd and Pb exposure were significantly (p <0.05) associated with SA. Conclusion: Zn and Cu deficiencies and Pb and Cd exposure were associated with abortion. Endocrine dysfunction, such as insulin resistance, vitamin D insufficiency, and abnormal thyroid and sex hormone concentrations, is thought to be involved in heavy metal-related abortion.


Assuntos
Aborto Espontâneo , Metais Pesados , Gravidez , Feminino , Humanos , Cádmio , Chumbo , Zinco
2.
Comput Intell Neurosci ; 2022: 5159448, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35720916

RESUMO

The current town ecological landscape planning and governance methods are mainly based on the high quality, high energy-saving, and environmental protection effect of the town ecological landscape. How to innovate the town ecological landscape planning and governance process with the help of Internet of things technology and fuzzy optimization method is the current development trend. Based on this, this paper studies the application of Internet of things technology in town ecological landscape planning and management. Firstly, a small town ecological landscape evaluation model based on fuzzy optimization algorithm is proposed. Combined with multivariate matrix transformation function, the authenticity data of ecological landscape are simulated. The original analysis of different types of small town ecological landscape is realized by selecting the multivariate extremum of autocorrelation function curve in the process of planning and governance. Secondly, in the simulation evaluation link, the fuzzy evaluation method is adopted and improved. At the same time, the improved three-dimensional original planning governance model is used to comprehensively analyze the simulation results of three-dimensional landscape planning governance. Finally, by designing fuzzy simulation experiments, the application effects of different Internet of things technologies in town ecological landscape planning and governance are analyzed. The experimental results show that the correlation data indicators of fuzzy optimization methods corresponding to different Internet of things technologies are very different. The application effect of different types of Internet of things technology in ecological landscape planning and governance of small towns is targeted and shows strong regularity.


Assuntos
Planejamento de Cidades , Internet das Coisas , Cidades , Conservação dos Recursos Naturais , Tecnologia
3.
Opt Express ; 24(12): 13325-33, 2016 Jun 13.
Artigo em Inglês | MEDLINE | ID: mdl-27410349

RESUMO

The leakage light of optical pulses due to finite extinction ratio (ER) of an electro-optic modulator (EOM) leads to Rayleigh backscattered noises over the entire fiber length, and limits spatial resolution and sensing range in phase-sensitive optical time-domain reflectometry (Φ-OTDR). Two configurations are proposed to improve the ER of optical pulses for better spatial resolution over long sensing length. With ER of 55 dB using a nonlinear optical loop mirror, we achieved 2 m spatial resolution over 8.4 km sensing length; while with ER of 60 dB obtained by two cascaded EOMs, we can achieve a 1 m spatial resolution over the same range. Experimental results and analysis show that leakage of the optical pulses acts as a noise floor, which limits the highest spatial resolution over the same sensing range.

4.
Opt Lett ; 41(6): 1138-41, 2016 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-26977653

RESUMO

We propose a unique multi-parameter optical fiber sensor based on intramodal stimulated Brillouin scattering of higher-order acoustic modes in inverse-parabolic graded-index fiber (IPGIF) without a mode converter. Both optical modes and acoustic modes guided in the IPGIF are characterized and demonstrated theoretically and experimentally. Simulation analysis shows that the multi-peak feature in the Brillouin gain spectrum of the IPGIF is attributed to the couplings between the guided optical mode and the higher-order acoustic modes. Thanks to the distinct acoustic properties of the peaks induced by the sharp refractive index profile of the IPGIF, the different temperature and strain dependences of the first three Brillouin peaks enable the discrimination of the temperature and strain at an accuracy of 0.85°C and 17.4 µÎµ.

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