1.
Chem Commun (Camb)
; 55(91): 13653-13656, 2019 Nov 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31593201
RESUMO
Blending synthetic biology and synthetic chemistry represents a powerful approach to diversity complex molecules. To further enable this, compatible synthetic tools are needed. We report the first Buchwald Hartwig amination reactions with unprotected halotryptophans under aqueous conditions and demonstrate this methodology is applicable also to the modification of unprotected tripeptides and the natural product barettin.